Israeli Arabs develop diverticulitis at a younger age and are more likely to require surgery than Jews

Abstract

BackgroundOnly few studies have examined the impact of racial differences on the age of onset, course and outcomes of diverticulitis.AimTo provide data about the epidemiology of diverticulitis in northern Israel, and to determine whether ethnicity is a predictor of age of onset, complications, and need for surgery.MethodsWas conducted a retrospective review of the charts of all patients diagnosed with a first episode of diverticulitis in our hospital between 2005 and 2012.ResultsWere found 638 patients with a first episode of acute diverticulitis in the eight year interval. Israeli Arabs developed a first episode of diverticulitis at a younger age compared to Jews (51.2 vs 63.8 years, p<0.01). Arabs living in rural areas developed diverticulitis at a younger age than Arabs living in urban centers (49.4 vs 54.5 years, P=0.03). Jewish and Arabic men developed diverticulitis at younger age compared to their female counterparts (59.9 vs 66.09, p<0.01, and 47.31 vs 56.93, p<0.01, respectively). Arabs were more likely [odds ratio (OR)=1.81 ,95% confidence interval (CI)1.12-2.90, p=0.017] than Jews to require surgical treatment (urgent or elective) for diverticulitis.ConclusionsIsraeli Arabs tend to develop diverticulitis at a younger age and are more likely to require surgical treatment for diverticulitis compared to Jews. Arabs living in rural areas develop diverticulitis at a younger age than Arabs living in urban centers. These findings highlight a need to address the root cause for ethnic differences in onset, course and outcome of acute diverticulitis.

Predictors of Clinical Course and Outcomes of Acute Diverticulitis: The Role of Age and Ethnicity

“…Of note, almost half of these patients presented with their first episode at ages younger than 50 years, one of the highest rates when compared to those reported in the literature for other various ethnicities [23]. These interesting findings match with a previous Israeli study conducted by Ghersin et al [24], in which Arabs tended to develop diverticulitis at a significantly younger age than Jews. Genetic, nutritional, microbiological, behavioral, and environmental factors may account for these findings.…”