Nutritional care in peptic ulcer

Vomero, Nathália Dalcin; Colpo, Elisângela

doi:10.1590/s0102-67202014000400017

Cited by 38 publications

(21 citation statements)

References 31 publications

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“…The fiber from wheat is mostly insoluble, and insoluble fibers are known to increase stool bulk, reduce transit time, and make fecal elimination easier and quicker. In this way, insoluble fiber can regulate bowel functions to promote the wellbeing of healthy people and can function as a remedy to alleviate several gastrointestinal diseases such as peptic ulcers and cancer (64,65).…”

Section: Discussionmentioning

confidence: 99%

Substituting whole grains for refined grains in a 6-wk randomized trial has a modest effect on gut microbiota and immune and inflammatory markers of healthy adults

Vanegas

Meydani

Barnett

et al. 2017

The American Journal of Clinical Nutrition

204

159

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Background: Observational studies suggest an inverse association between whole-grain (WG) consumption and inflammation. However, evidence from interventional studies is limited, and few studies have included measurements of cell-mediated immunity. Objective: We assessed the effects of diets rich in WGs compared with refined grains (RGs) on immune and inflammatory responses, gut microbiota, and microbial products in healthy adults while maintaining subject body weights. Design: After a 2-wk provided-food run-in period of consuming a Western-style diet, 49 men and 32 postmenopausal women [age range: 40-65 y, body mass index (in kg/m 2 ) ,35] were assigned to consume 1 of 2 provided-food weight-maintenance diets for 6 wk. Results: Compared with the RG group, the WG group had increased plasma total alkyresorcinols (a measure of WG intake) (P , 0.0001), stool weight (P , 0.0001), stool frequency (P = 0.02), and shortchain fatty acid (SCFA) producer Lachnospira [false-discovery rate (FDR)-corrected P = 0.25] but decreased pro-inflammatory Enterobacteriaceae (FDR-corrected P = 0.25). Changes in stool acetate (P = 0.02) and total SCFAs (P = 0.05) were higher in the WG group than in the RG group. A positive association was shown between Lachnospira and acetate (FDR-corrected P = 0.002) or butyrate (FDR-corrected P = 0.005). We also showed that there was a higher percentage of terminal effector memory T cells (P = 0.03) and LPS-stimulated ex vivo production of tumor necrosis factor-a (P = 0.04) in the WG group than in the RG group, which were positively associated with plasma alkylresorcinol concentrations. Conclusion: The short-term consumption of WGs in a weightmaintenance diet increases stool weight and frequency and has modest positive effects on gut microbiota, SCFAs, effector memory T cells, and the acute innate immune response and no effect on other markers of cell-mediated immunity or systemic and gut inflammation. This trial was registered at clinicaltrials.gov as NCT01902394.Am J Clin Nutr 2017;105:635-50.

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Section: Discussionmentioning

confidence: 99%

Substituting whole grains for refined grains in a 6-wk randomized trial has a modest effect on gut microbiota and immune and inflammatory markers of healthy adults

Vanegas

Meydani

Barnett

et al. 2017

The American Journal of Clinical Nutrition

204

159

View full text Add to dashboard Cite

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“…Studies have also shown a strong relationship between duodenal ulcer and HP 26 , 27 . They found duodenal ulcer as the most common injury in their papers.…”

Section: Discussionmentioning

confidence: 96%

“…It is known that the acquisition of this infection has interpersonal transmission, is related to socioeconomic and environmental factors, being more prevalent in developing countries 4 , 18 , 26 .…”

Section: Introductionmentioning

confidence: 99%

Relationship Between the Presence of Helicobacter Pylori With Inflammatory Endoscopic Changes in Gastroduodenal Mucosa

Ribeiro

Kubrusly

Nassif

et al. 2016

ABCD, arq. bras. cir. dig.

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Background: The influence of Helicobacter pylori (HP) in inflammatory disorders of the digestive mucosa has been the subject of several studies since socioeconomic, personal and environmental factors were implicated in the bacteria transmission. Aim: To correlate the inflammatory endoscopic findings with HP infection and the onset of mucosal diseases mucous of the upper digestive tract. Method: Comparative observational study, in which were collected data from 2247 patients who underwent upper endoscopy and biopsies for HP with urease test. The patients were divided into two groups: HP+ and HP- (control) in which endoscopic findings were observed for the following changes: esophagitis, esophageal ulcer, gastritis, erosive gastritis, gastric ulcer, bulboduodenitis, bulbar ulcer and without disease. Results: As for esophagitis, there was little disparity in the distribution favorable to HP+ group (HP+ =67.11% and HP- =69.89%) and esophageal ulcer (HP+ =0% and HP- =0, 21%). Gastritis was favorable to HP- group (HP+ =78.34% and HP- =73.63%), as well as erosive gastritis (HP+ = 67,11% and HP- = 64,55%), in bulboduodenitis (HP+ =1,87% and HP- 1,23%), in gastric ulcer (HP+ =2,14% and HP- =2,03%) and in the absence of alterations in the HP+ group (4.81%) with the HP- control group (6,30%), in which there was little disproportion in favor of HP- group, but without statistical significance. As for the bulbar ulcer (HP +=10.16% and HP- =4.48%), there was statistically significant (p=0.00001). Conclusion: There is no difference between HP+ and HP- groups in inflammatory changes in endoscopic gastroduodenal mucosa, except for the relationship between HP and bulbar ulcer.

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“…Peptic ulcer disease most often presents as either gastric or duodenal ulcer [3]. Racial difference has also been observed, and in Africa duodenal ulcers are found to be rare in black people, but in the United States the incidence is the same for blacks and whites; regarding gender, there is predominance of ulcers in males [4].…”

Section: Description Of Peptic Ulcer Diseasementioning

confidence: 99%

Peptic Ulcer in Veterinary Medicine: A Mini Review

AA¹

2019

IZAB

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Ulceration and discontinuity of the gastrointestinal mucosal can be a consequence of several drugs and diseases in small animals. As a result, gastroprotectant therapies are widely used in veterinary patients. Gastrointestinal ulcers can occur independently or as a complication of many systemic diseases hence have a significance importance to clinician in understand the etiological factors, pathophysiology for their effective treatment and early prophylaxis.

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Nutritional care in peptic ulcer

Cited by 38 publications

References 31 publications

Substituting whole grains for refined grains in a 6-wk randomized trial has a modest effect on gut microbiota and immune and inflammatory markers of healthy adults

Substituting whole grains for refined grains in a 6-wk randomized trial has a modest effect on gut microbiota and immune and inflammatory markers of healthy adults

Relationship Between the Presence of Helicobacter Pylori With Inflammatory Endoscopic Changes in Gastroduodenal Mucosa

Peptic Ulcer in Veterinary Medicine: A Mini Review

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