Tumor de células gigantes em falange proximal com metástase pulmonar: relato de caso e revisão de literatura

Medeiros, Frederico Carvalho de; Medeiros, Fernando Carvalho de; Lopes, Izabella de Campos Carvalho; Medeiros, Guilherme Carvalho de; Medeiros, Eduardo Carvalho de

doi:10.1590/s0102-36162011000200016

Cited by 3 publications

(4 citation statements)

References 15 publications

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“…Tendem a cursar com aumento do volume local e incapacidade funcional de forma precoce, principalmente pela superficialidade do tumor nessa localização e, proximidade, com a articulação. Podem ainda apresentar quadros mais exuberantes de dor por fraturas patológicas (3) e costumam evoluir com invasão das partes moles adjacentes sem invadir e ulcerar a pele e o tecido celular subcutâneo (2,5).…”

Section: Discussionunclassified

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Tumor De Células Gigantes Em Topografia De 4ª Falange Proximal: Relato De Caso

Silva

Filho

2021

Rease

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Objetivou-se, com esse trabalho, realizar o relato de caso de uma paciente do sexo feminino de 23 anos portadora de tumor de células gigantes (TCG) em 4º dedo da mão esquerda, acometendo por contiguidade a topografia de 3ª, 4ª e 5ª regiões metacarpo falangeanas. Paciente iniciou quadro de dor 8 meses antes do diagnóstico, evoluindo com tumoração local. Foi submetida a exames clínicos, exames radiográficos e ressonância magnética bem como a estudo histológico de material coletado a partir de biópsia incisional, que sugeriram o diagnóstico de TCG em 4ª falange proximal. Diante disso optou-se pelo tratamento cirúrgico de amputação dos dedos acometidos pelo tumor. A paciente evoluiu satisfatoriamente ao longo dos 5 anos subsequentes ao tratamento cirúrgico, sem recidivas locais ou metástases.

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Section: Discussionunclassified

“…Histologicamente é constituído de estroma com células ovalares ou fusiformes e numerosas células gigantes multinucleadas dispersas no entremeando tumoral. O tecido neoplásico costuma apresentar-se ricamente vascularizado embora com pouco substrato intercelular (3,5).…”

Section: Discussionunclassified

Tumor De Células Gigantes Em Topografia De 4ª Falange Proximal: Relato De Caso

Silva

Filho

2021

Rease

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“…On the other hand, if the WFP undergoes associations of this nature, as happened with açaí, it will lose its cultural connection. In the exemplary case, reaching international markets did not contribute to the biocultural conservation of the species, considering that the new consumers do not even know its origins or how the local population uses the fruit [88].…”

Section: Strategies For Popularizing Wfp: Cultural Identity X Associa...mentioning

confidence: 99%

“…For example, ʺThis is araçá juice, but it resembles guava juice." The popularization of açaí, for example, was greatly influenced by the power of the media, in which both TV and the internet collaborated in spreading the use of this fruit species [88,92]. Third, it is necessary to push for and assist in the sustainable management of WFP by integrating communities holding local ecological knowledge about these plants [93] into conservation projects so that this link between PAS and their biocultural heritage is perpetuated [94].…”

Section: Implications For Biocultural Conservationmentioning

confidence: 99%

Unconventional Names and Those Associated with Forest Environments Reduce Expectations about Juice - Contributions to the Valuation of Sociobiodiversity Products

Santos¹,

Barbosa²,

Gomes³

et al. 2023

Preprint

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Despite the global richness of food plants, only a small portion is used as food for humans. Although most wild food plants (WFPs) are underutilized as food, they can contribute to food security and biocultural conservation through sustainable management. The goal of this research was to identify the best terminological presentation of a novel food product and to understand the influences of the expectations on products with WFP. This research was conducted using an online questionnaire with a final national sample of 724 people. The participants answered questions about their socioeconomic profile, food neophobia, prior knowledge, and expectations regarding the taste and appropriateness of native fruit juices. The questions were randomized so that a person would not receive the same picture or product name more than once. The results show that taste expectancy decreases in relation to products associated with WFP names and forest environments. Food neophobia is the variable that influences expectations the most. To ensure biocultural conservation and cultural valuation, WFP popularization programs should maintain the original (popular) name of the species. However, to help more distant consumers develop familiarity, the flavor, shape, color, or texture of these products can be associated with those of conventional plants.

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The Evaluation and Management of Lung Metastases in Patients with Giant Cell Tumors of Bone in the Denosumab Era

Trovarelli,

Rizzo,

Cerchiaro

et al. 2024

Current Oncology

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Giant cell tumor of bone (GCTB) is characterized by uncertain biological behavior due to its local aggressiveness and metastasizing potential. In this study, we conducted a meta-analysis of the contemporary literature to evaluate all management strategies for GCTB metastases. A combination of the terms “lung metastases”, “giant cell tumor”, “bone”, “treatment”, and “oncologic outcomes” returned 133 patients meeting our inclusion criteria: 64 males and 69 females, with a median age of 28 years (7–63), at the onset of primary GCTB. Lung metastases typically occur at a mean interval of 26 months (range: 0–143 months) after treatment of the primary site, commonly presenting as multiple and bilateral lesions. Various treatment approaches, including surgery, chemotherapy, radiotherapy, and drug administration, were employed, while 35 patients underwent routine monitoring only. Upon a mean follow-up of about 7 years (range: 1–32 years), 90% of patients were found to be alive, while 10% had died. Death occurred in 25% of patients who had chemotherapy, whereas 96% of those not treated or treated with Denosumab alone were alive at a mean follow-up of 6 years (range: 1–19 years). Given the typically favorable prognosis of lung metastases in patients with GCTB, additional interventions beyond a histological diagnosis confirmation may not be needed. Denosumab, by reducing the progression of the disease, can play a pivotal role in averting or delaying lung failure.

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Tumor de células gigantes em falange proximal com metástase pulmonar: relato de caso e revisão de literatura

Cited by 3 publications

References 15 publications

Tumor De Células Gigantes Em Topografia De 4ª Falange Proximal: Relato De Caso

Tumor De Células Gigantes Em Topografia De 4ª Falange Proximal: Relato De Caso

Unconventional Names and Those Associated with Forest Environments Reduce Expectations about Juice - Contributions to the Valuation of Sociobiodiversity Products

The Evaluation and Management of Lung Metastases in Patients with Giant Cell Tumors of Bone in the Denosumab Era

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