Reexpansion pulmonary edema

Abstract

Reexpansion pulmonary edema (RPE) is a rare, but frequently lethal, clinical condition. The precise pathophysiologic abnormalities associated with this disorder are still unknown, though decreased pulmonary surfactant levels and a pro-inflammatory status are putative mechanisms. Early diagnosis is crucial, since prognosis depends on early recognition and prompt treatment. Considering the high mortality rates related to RPE, preventive measures are still the best available strategy for patient handling. This review provides a brief overview of the pathophysiology, diagnosis, treatment, and prevention of RPE, with practical recommendations for adequate intervention.

Protective efficiacy of taurine against pulmonary edema progression: experimental study

“…Re-expansion pulmonary edema (RPE) is an acute, rare and potentially lethal complication [ 1 , 2 ]. Its beginning is sudden and dramatic.…”

“…The RPE is a disease process that is characterized by diffuse inflammation in the lung parenchyma and resultant permeability edema [ 2 ]. The involvement of inflammatory mediators in RPE has been the subject of intense investigation, and oxidant-mediated tissue injury is likely to be important in the pathogenesis of RPE [ 2 ].…”

“…The RPE is a disease process that is characterized by diffuse inflammation in the lung parenchyma and resultant permeability edema [ 2 ]. The involvement of inflammatory mediators in RPE has been the subject of intense investigation, and oxidant-mediated tissue injury is likely to be important in the pathogenesis of RPE [ 2 ]. In response to various inflammatory stimuli, lung endothelial cells, alveolar cells, and airway epithelial cells, as well as alveolar macrophages, produce reactive oxygen species (ROS) [ 2 , 5 ].…”

Use Caution in Draining Effusions in Patients with Liver Disease

“…16 Reexpansion pulmonary edema has been studied, and there are some potential prevention recommendations available, including taking into account the duration of time the effusion has been present, the presence of underlying lung disease, the pleural pressure, and the presence of symptoms while doing the thoracentesis. 17 In general, consensus appears to be that less than 1.5 liters should be removed, unless pleural pressures are used for guidance.…”

Reexpansion Pulmonary Edema: analysis of eight

“…2,16,23 Klinik tablo genelde 1-2 saat içinde başlar, 24-48 saat içinde yavaş yavaş geriler ve en geç 5-7 gün arasında kendiliğinden veya medikal tedavi ile tamamen kaybolur. 2,5,[24][25][26] Bu çalışmada tüm olgularda klinik tablo müdahaleden 2 saat sonra başlamış, cerrahi müdahale sonrası düzelen periferik oksijen satürasyonu ve kan gazı değerlerinin, ikinci saatten itibaren yaklaşık dört-altı saat boyunca tedricen düştüğü ve solunum asidozu tablosu geliştiği tespit edilmiştir. Klinik tablo bir olguda progresif seyrederek 8. saatte hayatını kaybetmesine neden olmuş, diğer yedi olguda 72 saatten sonra gerilemeye başlamıştır.…”