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Cited by 88 publications
(62 citation statements)
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References 40 publications
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“…The dyes Sunset Yellow, Tartrazine and Red 40 are classified as azo food additives, because they have an azo group in their formulation, which is a nitrous derivative property to produce aromatic amine and sulfanilic acid (Sardi et al, 2010). These color additives have the potential to alter the turnover of cells during interphase and the regenerative hyperplasia process, contributing significantly to the development of digestive tract cancers in rodents (Polônio & Peres, 2009, Mpountoukas et al, 2010. These three azo dyes were also significantly cytotoxic, mutagenic and genotoxic to meristematic cells of Allium cepa roots (Gomes et al, 2013).…”
Section: Resultsmentioning
confidence: 99%
“…The dyes Sunset Yellow, Tartrazine and Red 40 are classified as azo food additives, because they have an azo group in their formulation, which is a nitrous derivative property to produce aromatic amine and sulfanilic acid (Sardi et al, 2010). These color additives have the potential to alter the turnover of cells during interphase and the regenerative hyperplasia process, contributing significantly to the development of digestive tract cancers in rodents (Polônio & Peres, 2009, Mpountoukas et al, 2010. These three azo dyes were also significantly cytotoxic, mutagenic and genotoxic to meristematic cells of Allium cepa roots (Gomes et al, 2013).…”
Section: Resultsmentioning
confidence: 99%
“…Moreover, Salinas (2002) and Polônio and Peres (2009) claimed that the use of flavorings in low doses does not pose risk to human health, however, at high dose levels, can cause annoying and narcotic actions and chronic cellular toxicity in the long term. Similarly, these authors do not specify which doses or concentrations of these additives are considered high or low.…”
Section: Groupmentioning
confidence: 99%
“…Allergies are included in these purposes is defined as a hypersensitivity reaction to allergens (antigens), among the dyes that can cause these effects highlight the tartrazine dye, amaranth, ponceau 4R, erythrosine and bright green 3 . Other effects have been evidenced in disorder and attention deficit hyperactivity disorder 25 , and deficit may also have mutagenic and carcinogenic effects, studies have shown that dietary factors can influence positively or negatively in the incidence of cancer, artificial dyes are listed potential carcinogens.…”
Section: "Don't My Biggest Difficulty Is Regarding Too Few Ingredienmentioning
confidence: 99%
“…Besides the modification of diet over the time, the food industry, in order to increase the shelf life of products, has used technology to their advantage, creating doubts on the safe use of food additives, particularly regarding the use artificial dyes. 3,4 According to ANVISA (1997):…”
Section: Introductionmentioning
confidence: 99%