2007
DOI: 10.1590/s0102-311x2007000700021
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Abstract: This study aimed to evaluate the impact of vaccination against Haemophilus influenzae type b (HIB) in Brazil on the morbidity, mortality, and case fatality of HIB meningitis, using the Ministry of Health database and population data from the Brazilian Institute of Geography and Statistics (Instituto Brasileiro de Geografia e Estatística -IBGE). Impact was evaluated through a time series analysis (1983)(1984)(1985)(1986)(1987)(1988)(1989)(1990)(1991)(1992)(1993)(1994)(1995)(1996)(1997)(1998)(1999)(2000)(2001)(2… Show more

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Cited by 10 publications
(7 citation statements)
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“…In turn, the incidence of cases caused by S. pneumoniae remained stable over the study period. With regards to meningitis caused by H. infl uenzae type b, the number of cases decreased in State of Amazonas as well as on a national scale, owing to the introduction of the anti-Hib vaccine in 1999-2000 (22) (23) (24) .…”
Section: Discussionmentioning
confidence: 99%
“…In turn, the incidence of cases caused by S. pneumoniae remained stable over the study period. With regards to meningitis caused by H. infl uenzae type b, the number of cases decreased in State of Amazonas as well as on a national scale, owing to the introduction of the anti-Hib vaccine in 1999-2000 (22) (23) (24) .…”
Section: Discussionmentioning
confidence: 99%
“…The introduction of Hib vaccination significantly reduced the incidence of invasive disease caused by H. influenzae in several high-income and developing countries [22][24]. In Brazil, a surveillance study carried out in Salvador, Bahia, demonstrated a considerable reduction in the incidence of Hib meningitis mainly in children below one year of age (from 60.9 to 3.1 cases per 100,000 population) [25].…”
Section: Discussionmentioning
confidence: 99%
“…48 As in many places with high vaccine coverage, the incidence of and mortality from meningitis caused by H infl uenzae type b in children younger than 5 years sub stantially decreased after the introduction of the Hib vaccine to the routine schedule in 1999. 49,50 Although, in general, vaccine coverage in Brazil is very high, it is not uniform across socioeconomic levels, with lowest coverage in the highest and lowest socioeconomic groups (fi gure 2).…”
Section: Successful Control Vaccine-preventable Diseasesmentioning
confidence: 99%