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Cited by 17 publications
(16 citation statements)
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References 44 publications
(43 reference statements)
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“…The anti-androgenic effects of selected pesticides are well-defined from in vivo studies [57], and are important in light of the androgen-dependent normal urethral development in the fetus [2,9,28,58]. It is also possible that estrogenic or other endocrine-disrupting effects of pesticides play a role [8,59—61].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The anti-androgenic effects of selected pesticides are well-defined from in vivo studies [57], and are important in light of the androgen-dependent normal urethral development in the fetus [2,9,28,58]. It is also possible that estrogenic or other endocrine-disrupting effects of pesticides play a role [8,59—61].…”
Section: Discussionmentioning
confidence: 99%
“…Because sex hormones play a strong role in fetal genitourinary development [3,7], it has been hypothesized that in utero exposure to endocrine-disrupting chemicals could contribute to hypospadias [8,9]. Such chemicals might have an estrogenic or androgen-antagonist effect [8].…”
Section: Introductionmentioning
confidence: 99%
“…Potential adverse outcomes in humans are mostly described as effects on reproductive and sexual development and function [8,9], such as decreased sperm quality and increase in subfertility [10][11][12][13][14], changes in sex ratio [15,16], puberty disorders and higher incidence of cryptorchidism and hypospadias [9,12,15,[17][18][19].…”
Section: Introductionmentioning
confidence: 99%
“…Over the last twenty years, multiple behavioral and reproductive alterations have been observed in wildlife: altered fertility or gonadal development in fishes [1], mollusks, birds, and mammals [2,3,4,5,6] or sex-reversal of fishes living in polluted waters [7]. In humans, a decrease in male fertility has been observed, most prominently in specific types of professional, and an increase in sex-related cancers (breast, testis, prostate...) [8,9].…”
Section: Introductionmentioning
confidence: 99%