Determination of diflubenzuron residues in milk and cattle tissues

Abstract

Diflubenzuron (DFB) is used to control ectoparasitic infestation by inhibiting larvae development in the manure and feces of treated animals. It is also currently been used to control tick infestations. In this study, milk and tissues from cattle treated orally with DFB for a 77-120 day period with a commercial product containing the compound were analyzed for the presence of residues. DFB residues were determined by using extraction with acetonitrile, cleanup with C18 SPE and chromatographic analysis by HPLC with UV detection (254nm). DFB was not detected in any of the analysed samples (<0.006mg kg Palavras-chave: diflubenzurom, larvicida, droga veterinária, tecido bovino, leite

Human health risks associated with residual pesticide levels in edible tissues of slaughtered cattle in Benin City, Southern Nigeria

“…Aldrin, dieldrin and endrin are known to be closely related organochlorine pesticides that are extremely persistent in the environment [72] . Despite the ban of these organochlorines [1] , residual concentrations have been reported in tissues of food animals [62] , [56] , [105] , [36] , [97] , [103] . Concentrations of aldrin, dieldrin and endrin varied in the tissues: Muscle = Dieldrin > Aldrin > Endrin, Liver = Dieldrin > Endrin > Aldrin; Kidney = Aldrin > Endrin > Dieldrin; Tongue = Endrin > Aldrin > Dieldrin ( Table 1 , Fig.…”

“…Although residual levels of pesticides in meat and meat products have been documented [68] , [62] , [56] , [59] , [105] , [36] , [97] , [5] , information concerning dietary intake of pesticide residues from meat are limited [76] . [24] estimated dietary intake of γ-HCH and ∑DDT from consumption of meat products (beef, pork, lamb, poultry, cured/processed meats) from different cities in Sweden to be 0.0828 and 0.00949 μg/kg bw/d respectively which were however higher than concentrations observed in this study.…”

“…Concerns however has been raised over the accumulation of pesticides in tissues of livestock animals that serve as food especially cattle [70] , [76] . Although residual levels of pesticides in meat and meat products have been documented [62] , [56] , [105] , [36] , [97] , [5] , information concerning human health risk associated with consumption of meat contaminated with pesticide residues is scarce [76] .…”

Development of a kinetic spectrophotometric method for insecticide diflubenzuron determination in water and baby food samples

“…Many analytical methods for determination of diflubenzuron in food, feed and biological matrices have been reported. Due to the high polarity, low volatility and thermolability of diflubenzuron, HPLC has been the method of choice using UV [2][3][4][5][6], FD [7][8][9], MS [10][11][12][13][14], DAD [15] or fluorescence [16][17][18] detection. LC-MS/MS has been used for DFB determination in apple, tangerine and honey samples [19,20].…”

Rapid residue analysis of pyriproxyfen, avermectins and diflubenzuron in mushrooms by ultra-performance liquid chromatography coupled with tandem mass spectrometry

“…In addition, diubenzuron has been detected in fruits, milk and cattle tissues by high performance liquid chromatography (HPLC) with UV detection. 22,23 Mushrooms are different from these matrices: in that they contain plenty of protein and amino acids compared with vegetables and fruits; moreover levels of vitamins are higher than in vegetables and fruits. Recently, analytical methods of avermectin residues have been developed in animal liver and muscle by HPLC with a uorescence detector, 24,25 and in swine liver, water, sediments and soils by liquid chromatography-mass spectrometry with atmospheric pressure chemical ionization (APCI).…”