Anticoccidial efficacy of drinking water soluble diclazuril in the control of Eimeria acervulina oocysts on experimentally-infected broiler chickens

Assis, R.C.L.; Cury, Márcia Cristina; Luns, F. D.; Assis, Ricardo Luís de Aguiar

doi:10.1590/s0102-09352012000500016

Cited by 4 publications

(4 citation statements)

References 13 publications

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“…The lowest average body mass was recorded in chickens treated with both anticoccidials (Ro+Herb). Our results of increased weight gain and body weight in broilers treated with both the synthetic and herbal anticoccidials are in line with some previous data and resulted from their beneficial effects [29,31] . Positive effects on production performance resulting from the use of chemical and herbal anticoccidials have already been described [32] .…”

Section: Discussionsupporting

confidence: 92%

Antikoksidiyal Maddelerin Eimeria Türleri İle Enfekte Etlik Piliçlerde Oksidatif Stres, Üretim Performansı ve Dışkı Oosit Sayıları Üzerine Etkisi

Pajić́¹,

Aleksić²,

Vejnović³

et al. 2018

Kafkas Univ Vet Fak Derg

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The influence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine, the 2 nd a herbal anticoccidial (Herb) and the 3 rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST), and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram, and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P<0.05), whilst the activity of SOD was higher in infected chickens treated with anticoccidials (P<0.05) in comparison to those untreated. The most prominent change in the parameters of oxidative stress was recorded in the Ro+Herb group. In chickens treated with anticoccidials body weight was significantly higher (P<0.05), and the FCR and the oocyst counts significantly lower (P<0.05) than in untreated chickens. Oocyst counts were lower in the Ro and Ro+Herb groups than in the Herb group. Our study demonstrated that both anticoccidial substances exerted antioxidant and anticoccidial effects.

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Section: Discussionsupporting

confidence: 92%

Antikoksidiyal Maddelerin Eimeria Türleri İle Enfekte Etlik Piliçlerde Oksidatif Stres, Üretim Performansı ve Dışkı Oosit Sayıları Üzerine Etkisi

Pajić́¹,

Aleksić²,

Vejnović³

et al. 2018

Kafkas Univ Vet Fak Derg

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“…This indicated that the broilers immunologically responded to the developmental stages of the parasites at different intensities or time, resulting in varied oocyst output. The observed gradual reduction in oocyst output in the treated and non-treated experimental broilers from primary-secondary -tertiary infections is similar to the report of Assisi et al [18]. These authors reported that this may be due to the stimulation and production of immune bodies (T and B cells) in the non-treated broilers at primary and secondary infections and action of Amprolium in the treated chickens.…”

Section: Discussionsupporting

confidence: 89%

“…The varied prepatent periods associated with the infection, the unsporulated oocyst, sporulated oocyst, schizonts, merozoites and gametocytes which were 0, 120, 264, 96 and 48 h respectively are similar to the reports of Assisi et al [18] who also recorded 120 h prepatent period for birds infected with sporulated oocyst of Eimeria tenella. However the prepatent periods are inconsistent with the other stages of the parasite.…”

Section: Discussionsupporting

confidence: 86%

The Infectivity of Exo and Endogenous Stages of Eimeria tenella in Broilers

Kaze¹,

Lawal²,

Joseph³

et al. 2017

J immuno Biol

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Eimeria tenella is the most prevalent and pathogenic Coccidia causing morbidity, mortality and resulting in serious economic losses to the poultry industry worldwide. The aim of this study was to determine the immune response of broiler chickens to Eimeria tenella developmental stages Four hundred broilers divided into six groups (n=40) were used for the study. Each group was subdivided into two (n=20) as treated and non-treated and infected with different developmental stages (groups I-unsporulated oocysts, II-sporulated oocysts, III-schizonts, IV-merozoites and Vgametocytes respectively) of Eimeria tenella (local isolate), except group VI-control. The molecular identification of the local Eimeria tenella isolate identity was done through polymerase chain reaction (PCR) amplification of the genomic deoxyribonucleic acid (DNA). Clinical signs, gross caecal lesions, humoral and cellular-mediated immune response were determined in the infected broiler chickens with Eimeria tenella developmental stages. The faeces were processed using simple floatation technique and observed at 10x and 40x objectives of the Neiss microscope. Oocysts isolated from the caeca of birds naturally infected in Jos, Nigeria with the local strain were used to obtain the different developmental stages either in vitro or in vivo using bovine monocytes (schizonts), embryonated chicken eggs (gamatocytes) or two weeks old broilers (merozoites). To study the immune response elicited during the primary and secondary infection, each developmental stage was used to infect a group of two, three and half weeks old broilers, twenty of which were treated with the recommended dose of amprolium (250 mg/l (0.025%)) for 5 days at the appearance of clinical signs. At the tertiary infection, all the experimental birds except the control group of forty birds were orally infected with 105 sporulated oocysts of known characterized virulent Eimeria tenella strain. The mean oocysts output or count was 37.07 × 10 6 in the infected birds non-treated than 25.65 × 10 6 in the treated groups, although there was a gradual reduction (groups

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“…After viewing the symptoms of the infected animals like general weakness, bloody diarrhea and no interest in feeding, stool samples are taken to be tested microscopically using both direct smear and floating ways to examine the ovarian cysts. The infection level is to be determined by Assis et al, 2012 that depends on counting the number of those ovarian cysts in the sample in the slide, then calculating the cysts numbers per 1 gm stool multiplied by 10 and counting them by the microscope [23].…”

Section: Lab Testsmentioning

confidence: 99%

Relationship between coccidiosis and lipid peroxidation ‎level in blood of cattle.‎

Sadoon¹

2021

CBERJ

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Bovine coccidiosis is one of the most common diseases in livestock, which leads to large economic losses in addition to high mortality for animals, and despite the large number of studies on this disease, studies on the biochemical and physiological effects of this parasite are still limited, especially the effect of parasite infection on some variables Blood in cows, and from this standpoint the current study was conducted, which included measuring the levels of malondaldehyde ) MDA) , and glutathione(GSH) .As the study included a number of adult cows (40) and a number of young calves 2-3 months old (35 calves). A stool sample (5 grams) and a blood sample (10 cm) were taken from each animal. The affected animals were diagnosed through the detection of the visible symptoms on animal and stool examination The stool was laboratory treated through an examination, using floatation and direct smaer methods to find ovarian cysts of the parasite,and the percentage of infection was determined using the modified Macmaster method, and then biochemical tests were performed on blood samples of both infected and healthy cows.The color test method was used to measure the level of malondialdehyde and the modified Almanns method to measure the level of glutathione in plasma. The results of the current study showed that infection with the parasite increased lipid peroxidation in the blood plasma of both calves and cows, respectively (4.3423 ± 1.0238, 7.4918 ± 1.4232) compared with normal cows and calves (2.3423 ± 0.465, 2.9537 ± 1.063), while it led to a decrease in glutathione level in Both of the infected cows (7.3041 ± 2.8213) compared with healthy cows (11.2322 ± 2.2628), and there was no significant difference in the level of glutathione between infected and uninfected calves.

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Anticoccidial efficacy of drinking water soluble diclazuril in the control of Eimeria acervulina oocysts on experimentally-infected broiler chickens

Cited by 4 publications

References 13 publications

Antikoksidiyal Maddelerin Eimeria Türleri İle Enfekte Etlik Piliçlerde Oksidatif Stres, Üretim Performansı ve Dışkı Oosit Sayıları Üzerine Etkisi

Antikoksidiyal Maddelerin Eimeria Türleri İle Enfekte Etlik Piliçlerde Oksidatif Stres, Üretim Performansı ve Dışkı Oosit Sayıları Üzerine Etkisi

The Infectivity of Exo and Endogenous Stages of Eimeria tenella in Broilers

Relationship between coccidiosis and lipid peroxidation ‎level in blood of cattle.‎

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