Effect of mannanoligosaccharides and/or enzymes on antibody titers against infectious bursal and Newcastle disease viruses

Abstract

The effect of including mannanoligosaccharides (MOS) and/or enzymes in broiler diets on antibody titers against infectious bursal disease virus (IBDV) and Newcastle disease virus (NDV) was evaluated. A total of 750 broilers were distributed into a completely randomized experimental design in a factorial arrangement 2 x 2 + 1 with two levels of MOS (0 and 0.1% until 21 days and 0.05% from 22 to 42 days of age), two levels of enzymes (0 and 0.05%) and a positive control diet containing antibiotic, totaling five treatments with five replicates each. For antibody analyses, blood samples were weekly collected by jugular vein puncture in the same two birds per replicate. The first and last collections were done at 7 and 42 days of age, respectively. The inclusion of MOS resulted in increased antibody titers against IBDV in the fourth (P<0.03) and fifth (P<0.02) weeks, and against NDV in the third (P<0.01), fourth (P<0.03) and fifth (P<0.03) weeks of age. MOS was effective in stimulating the humoral immune responses against IBDV and NDV vaccine viruses.Keywords: broiler, additive, humoral immune modulation, prebiotic (0 e RESUMO O efeito da inclusão de mananoligossacarídeo (MOS) e/ou enzimas em dietas de frangos sobre os títulos de anticorpos contra os vírus das doenças de Gumboro (VDG) e de Newcastle (VDN). Setecentos e cinqüenta aves foram distribuídas em um delineamento experimental inteiramente ao acaso, em arranjo fatorial 2 x 2 + 1, com dois níveis de MOS

Effect of Using an Anticoccidial and a Prebiotic on Production Performances, Immunity Status and Coccidiosis in Broiler Chickens

“…Prebiotics and ionophores used to prevent coccidiosis can indirectly stimulate the immunity in post vaccination of poultry against certain immunosuppressive diseases affecting the lymphoid organs or against infections predisposing to coccidiosis such as Marek's disease which affects the T cell response (Morimura et al, 1995). Thus, the MOS enhances the immune response by increasing the antibody titer during vaccination against infectious bursal disease (Oliviera et al, 2009) and Newcastle disease (Gomez-Verduzco et al, 2009a;Oliviera et al, 2009).…”

“…They are mainly based on the preservation of the intestinal barrier integrity and the stimulation of the immune response. This is the case of some yeasts and their derivatives (Elmusharaf et al, 2007;Gomez-Verduzco et al, 2009a, b;Oliviera et al, 2009;Swiatkiewicz et al, 2014). Thus, the use of feed additives that prevent diseases such as coccidiosis and promote the nutrients utilization is important.…”

Stalboekje Pluimvee 2017 : Handboek voor natuurlijke pluimveegezondheidzorg met kruiden en andere natuurproducten

“…Gistcelwanden bevatten mannanoligosacchariden (MOS) die in staat zijn om ziekteverwekkers, zoals een groot aantal Salmonella en Escherichia coli stammen, te binden (Ferket et al, 2002). Daarnaast ondersteunen ze het immuunsysteem (Oliviera et al, 2009) en bevorderen ze de groei van gunstige darmbacteriën (Baurhoo et al, 2007).…”

Microbiotechnology Based Surfactants and Their Applications

“…Structural mannoproteins are the most abundant and are composed of a small protein portion linked to a greater carbohydrate portion (mannopyranosyl) while enzymatic mannoproteins have more protein moieties in their structures. These molecules are not only effective emulsifiers but have been associated with stimulation of host immunity by activating immune cells and proteins as well as triggering the production of antibodies (Casanova et al, 1992;Oliveira et al, 2009). A mannoprotein bioemulsifier from Kluyveromyces marxianus has been reported to form a 3-month old stable emulsion in corn oil (Lukondeh et al, 2003).…”