Enterotoxemia em bovino

Lobato, Francisco Carlos Faria; Assis, Ronnie Antunes de; Abreu, V.L.V.; Júnior, Milton Formiga Souza; Lima, C.; Salvarani, Felipe Masiero

doi:10.1590/s0102-09352006000500037

Cited by 5 publications

(5 citation statements)

References 6 publications

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“…The histotoxic group includes diseases such as blackleg (Clostridium chauvoei), malignant edema (Clostridium novyi type A, Clostridium perfringens type A, Clostridium sordelli, Clostridium septicum), and bacillary hemoglobinuria (Clostridium haemolyticum). The group of enteric diseases includes several types of necrotizing and hemorrhagic enteritis (Clostridium difficile in calves, C. perfringens type C, C. perfringens type E) and enterotoxemia (C. perfringens type D) which occurs in small ruminants and possibly in cattle (Uzal et al 2002, Lobato et al 2006, Filho et al 2009, Mete et al 2013.…”

Section: Introductionmentioning

confidence: 99%

Clostridial diseases diagnosed in cattle from the South of Rio Grande do Sul, Brazil. A forty-year survey (1978-2018) and a brief review of the literature

et al. 2019

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Clostridial diseases are important causes of livestock losses in the southern Rio Grande do Sul. Since 1978 annual surveys conducted at the “Laboratório Regional de Diagnóstico” of the “Universidade Federal de Pelotas” (LRD-UFPel) have shown that clostridial diseases represent 10.40% of the bacterial diseases diagnosed in cattle and 1.65% of all diseases diagnosis in cattle over a 40-year period. The purpose of this study is to review the clinical, epidemiological and pathological aspects of the clostridial diseases diagnosed in cattle from January 1978 to December 2018 at the LRD-UFPel in the hopes that it will constitute a useful guide for field veterinary practitioners and interested farmers. We assessed and review the necropsy protocols of 6,736 cattle; these necropsies were performed either by LRD-UFPel faculty or by field veterinary practitioners; 111 outbreaks (1.65%) were diagnosed as clostridial disease, distributed as follows: 35 outbreaks of tetanus, 34 of blackleg, 23 of bacillary hemoglobinuria, 11 of malignant edema (gas gangrene), and eight of botulism. Approximately 904, from a total of 42,480 cattle at risk, died in these outbreaks.

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Section: Introductionmentioning

confidence: 99%

Clostridial diseases diagnosed in cattle from the South of Rio Grande do Sul, Brazil. A forty-year survey (1978-2018) and a brief review of the literature

et al. 2019

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“…In sheep, type D is widely regarded as the causative agent of fatal enterotoxemia or "overeating disease" (3), but is also important in calves, goats and adult cattle (1). In Brazil, Lobato et al (6) reported the detection of C. perfringens type D in a bovine enterotoxaemia case, but C. perfringens typing has been rarely described in the country.…”

Section: Introductionmentioning

confidence: 99%

Genotyping of Clostridium perfringens associated with sudden death in cattle

Miyashiro¹,

Baldassi²,

Nassar³

2009

J. Venom. Anim. Toxins incl. Trop. Dis

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Toxigenic types of Clostridium perfringens are significant causative agents of enteric disease in domestic animals, although type E is presumably rare, appearing as an uncommon cause of enterotoxemia of lambs, calves and rabbits. We report herein the typing of 23 C. perfringens strains, by the polymerase chain reaction (PCR) technique, isolated from small intestine samples of bovines that have died suddenly, after manifesting or not enteric or neurological disorders. Two strains (8.7%) were identified as type E, two (8.7%) as type D and the remainder as type A (82.6%). Commercial toxoids available in Brazil have no label claims for efficacy against type E-associated enteritis; however, the present study shows the occurrence of this infection. Furthermore, there are no recent reports on Clostridium perfringens typing in the country

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“…Briefly, 1 mL of epsilon standard antitoxin was incubated at 37 °C for 1 hour with 1 mL of each filtered intestinal content in a 1:1 dilution. Then, Swiss Webster mice weighing 18-22 g were intravenously inoculated with 0.2 mL of each sample and subsequently observed for 72 hours for survival, according to the methods of Tammemagy and Grant (1967) and Lobato et al (2006).…”

Section: Seroneutralizationmentioning

confidence: 99%

Outbreak of Clostridium perfringens type D enterotoxemia in sheep

Salvarani

Faccin

Freitas

et al. 2019

SCA

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This work describes the first Brazilian laboratory-confirmed outbreak of enterotoxemia caused by Clostridium perfringens type D in sheep, which occurred in the state of Paraná. We address the epidemiological aspects involved, the diagnostic modalities employed, and the clinical signs and pathological findings observed. Eight healthy pregnant female sheep with no history of vaccination for clostridiosis presented with a history of abrupt feeding changes and neurological manifestations that quickly evolved to illness, coma and death. Four other females with clinical neurological signs were referred to the Veterinary Hospital of the Universidade Federal do Paraná, Palotina Sector. These animals presented with lethargy, motor incoordination, opisthotonus, pedal movements, muscle tremors, spastic paralysis, bruxism, mandibular trismus, sialorrhea, hyperexcitability and the inability to stand. They were examined and euthanized due to the seriousness of the clinical picture with an unfavorable prognosis. We performed gross anatomical and microscopic analyses of the organs and intestinal contents. We also performed bacterial isolation with molecular typing. From the intestinal contents, we detected toxins by means of the seroneutralization technique in mice. At necropsy, we noted pulmonary edema (2/4), necrotizing enteritis (4/4) and hyperemia of the leptomeninges (1/4). Microscopically, we observed lymphohistiocytic interstitial pneumonia, necrotic enteritis associated with the presence of rods, and nephrosis with interstitial lymphohistiocytic nephritis. No significant brain lesions were observed. Using serum neutralization, we identified epsilon toxin in the intestinal contents of all four animals. C. perfringens type D was identified. Based on the history, clinical signs, postmortem findings, and laboratory confirmation of the presence of epsilon toxin, we concluded that C. perfringens type D enterotoxemia caused this outbreak of sheep deaths.

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Enterotoxemia em bovino

Cited by 5 publications

References 6 publications

Clostridial diseases diagnosed in cattle from the South of Rio Grande do Sul, Brazil. A forty-year survey (1978-2018) and a brief review of the literature

Clostridial diseases diagnosed in cattle from the South of Rio Grande do Sul, Brazil. A forty-year survey (1978-2018) and a brief review of the literature

Genotyping of Clostridium perfringens associated with sudden death in cattle

Outbreak of Clostridium perfringens type D enterotoxemia in sheep

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