Serum concentrations of creatine kinase and of triglycerides during lactation in gilts bred older and in multiparous sows fed ad libitum

Abstract

The aim of this paper was to assess the possible variation in blood concentrations of creatine kinase (CK) and triglycerides in gilts bred older in comparison with multiparous sows. Ten primiparous and ten Camborough multiparous sows from the fourth to seventh parities were used. Breeding age and weight of gilts averaged respectively 231 days and 149.5kg. All females were moved into individual farrowing crates and were managed under the same conditions. Blood samples were collected by puncturing the coccygeal artery on day 7 before expected farrowing, and on days 2, 7, 14, 21 of lactation and 2 days after weaning. No difference in triglycerides and CK serum concentrations between groups were observed. The CK levels were low before farrowing, increased substantially on days 2 and 7 and decreased toward the end of lactation. The concentrations of triglycerides were slightly high before the parturition, diminished on days 2, 7, 14 and 21 and increased after weaning.

Characterization of plasma metabolites at late gestation and lactation in early parity sows on production and post-weaning reproductive performance1

“…Second-parity dams had similar CPK activity at WN to first-parity dams, but second-parity WN values were not different from d110G measurements of second-parity dams. The abrupt change in plasma concentrations of CPK was not surprising, as sharply increased levels of CPK activity following parturition has been reported in women (Abramov et al, 1996;Conner et al, 2006) and primi-and multi-parous sows (Nogueira et al, 2000). The dramatic increase in CPK activity observed in the current study was likely the result of uterine ischemia and reperfusion injury due to parturition since the activity levels at weaning were similar to or less than late gestation values.…”

Safety Evaluation of a Standardized <i>Macleaya cordata</i> Extract in a Ninety Day Feeding Study in Weaned Piglets

“…In general, an increase in CK activity indicates muscle damage, while a decrease has been known to occur from muscle wasting [27]. However, the T4 group did not have a significant decrease in body weights, and CK levels did not correlate with serum creatinine levels.…”

Effects of post-partum administration of ketoprofen on sow health and piglet growth

“…Parturition itself increases serum AST and CK activities (Nogueira et al, 2000;Nathwani et al, 2005). AST increased with ketoprofen use across all parities on day 5 p.p.…”

“…Parturition can cause external symptoms of malaise with tissue breakdown and inflammation. Tissue damage can be detected as increased serum aspartate aminotransferase (AST) and creatinine kinase (CK) activity, which are both released from damaged muscle cells (Nogueira et al, 2000). Acute phase proteins (APPs), such as haptoglobin (Hp) and serum amyloid A (SAA) concentrations increase during the inflammatory processes (Chen et al, 2003;Heinonen et al, 2010), and during the puerperium period (Verheyen et al, 2007;Papadopoulos et al, 2009).…”