Mixossarcoma em mesentério de cão

Oliveira, Simone Tostes de; Cunha, Cristina; Iwanaga, Soji; Coelho, Humberto Eustáquio; Manzan, Roberto Martins

doi:10.1590/s0102-09351999000600005

Cited by 4 publications

(5 citation statements)

References 3 publications

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“…Um estudo retrospectivo mostra que os principais tipos histológicos de neoplasma encontrados nesse sistema são adenocarcinomas, linfomas, leiossarcomas, sarcomas e adenomas, não encontrando nenhum caso de mixossarcoma (LEANDRO, 2010). Até o momento, a única descrição relacionada ao trato digestório nessa espécie se localiza no mesentério (OLIVEIRA et al, 1999). Outros relatos verificam sua ocorrência em pele (FERNANDES et al, 2015), coração (ADISSU et al, 2010), vesícula urinária (BRAZ et al, 2015, musculatura abdominal (NEGREIROS et al, 2014) e baço (SPANGLER et al, 1994BANDILELLI, 2001).…”

Section: Resultsunclassified

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I Simpósio de Ciência Animal e II Fórum de Veterinária e Zootecnia do IF Goiano

Malafaia

2018

MSJ

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Section: Resultsunclassified

“…A pele, glândulas mamárias, sistema genital e trato digestório, respectivamente, são os locais de sua maior ocorrência (ANDRADE, 2012). Dentre os diversos tipos encontrados, o mixossarcoma se destaca pela sua raridade e capacidade de se desenvolver em diferentes partes do organismo que tenha tecido conjuntivo (OLIVEIRA et al, 1999).…”

Section: Introductionunclassified

I Simpósio de Ciência Animal e II Fórum de Veterinária e Zootecnia do IF Goiano

Malafaia

2018

MSJ

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“…O mixossarcoma é uma neoplasia de ocorrência pouco frequente em cães, correspondendo a 0,5% dos casos de tumores cutâneos e 2,3% dos casos de sarcomas de tecidos moles de cães e gatos [14,15]. Apesar de normalmente ser encontrado na forma subcutânea devido a sua origem fibroblástica, há relatos do tumor originando-se no mesentério, vísceras e olhos [1,6,9,11,18].…”

Section: Discussionunclassified

Radiographic, Citomorphological, and Histochemical Characterization of the Skin Mixosarcoma in a Bitch

Sampaio

Silva

Lima

et al. 2018

Acta Scientiae. Vet.

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Background: Myxosarcoma is a malignant mesenchymal tumor that arises from fibroblasts and is characterized by a low frequency of metastases, which in turn are highly invasive locally. Even though this type of tumor is relatively well documented, its radiographic and cytomorphological aspects are rarely described. The present report describes a case of cutaneous myxosarcoma in a female dog, and highlights radiographic, cytological, and histopathological findings. Case: An 11-year-old female mongrel dog was examined at the Veterinary Hospital of Federal University of Paraíba. The patient exhibited a firm 20 cm-wide mass covered by skin in the left abdominal wall, a lesion that had been developing for approximately five months. During the clinical examination, the patient demonstrated apathy and difficulty to stand. Initially, exams requested included radiography, ultrasonography, and cytological analysis of biopsy material obtained by fine needle aspiration (FNA). Radiography and ultrasonography were used to investigate the extent of the tumor, as well as invasion of other organs. Radiography revealed that the tumor was radiopaque, homogeneous, and restricted to the skin and subcutaneous tissue; no metastases were observed. Cytological examination allowed observation of a hypocellular sample predominantly composed of isolated pleomorphic fusiform cells embedded in a discrete homogeneous eosinophilic material. These cells exhibited a moderate, well delimited cytoplasm with multiple vacuoles; the end opposed to the nucleus was slender. Their nuclei were eccentric, with punctate chromatin and inconspicuous nucleoli. The patient was subjected to complete surgical excision of the tumor, and the surgical piece was submitted to histopathological examination. The mass was described as single and firm; its dimensions were 20 cm x 16 cm x 15 cm, and its weight was 2.5 kg. Fragments were processed and stained with hematoxylin and eosin (HE) or alcian blue (AB) for evaluation by optical microscopy. Histopathology revealed an infiltrative, expansive, non-encapsulated mass characterized by mesenchymal cells ranging from elongated to stellate. These cells were well individualized, had a scant to moderate cytoplasm, indistinct and slightly eosinophilic borders, and a nucleus that varied from oval to stellate in shape, with highly condensed chromatin and inconspicuous nucleoli. AB-stained specimens exhibited an extensive myxomatous matrix stained in blue, which was intertwined with neoplastic cells. Therefore, the diagnosis of cutaneous myxosarcoma was confirmed. Discussion: The diagnosis of myxosarcoma was established on the basis of radiographic and cytological findings, and it was confirmed by histopathological examination, which sped up decision-making and completion of the case. Tumors of this group are not accompanied by paraneoplastic syndromes; however, given the size and weight of the mass under study, pain may have been the triggering factor of the apathy and difficulty to stand observed here. The age of the patient and t...

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“…Myxosarcomas, also called fibromyxosarcomas, are malignant neoplasms derived from fibroblasts or other primitive mesenchymal cells that produce prominent extracellular matrix composed of mucin (BERMAN et al, 1992;GOLDSCHMID;SHOFER, 1992;OLIVEIRA et al, 1999;HENDRICK, 2002).…”

Section: Introductionmentioning

confidence: 99%

“…This neoplasm may occur at any site, but at least in dogs they occur most frequently in the skin. However, visceral organs such as heart, liver, spinal canal, and mesentery may also be affected (BERMAN et al, 1992;SHOFER, 1992;OLIVEIRA et al, 1999;HENDRICK, 2002;GROSS et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Cutaneous myxosarcoma in a Syrian hamster (Mesocricetus auratus)

et al. 2011

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The pathological findings in a 2-years-old Syrian hamster (Mesocricetus auratus) with a cutaneous myxosarcoma are described. Grossly, there was a large cutaneous mass in the right cervical region. Microscopical evaluation revealed a myxosarcoma characterized by pleomorphic, fusiform cells loosely arranged, randomly distributed, and presenting a moderate amount of basophilic amorphous stroma. There were hemorrhagic areas within the tumor. The basophilic amorphous stroma was positive to Alcian blue confirming the presence of a mucopolysaccharide matrix. Immunohistochemically, the neoplastic cells expressed vimentin, and were negative for cytokeratin or glial fibrillary acidic protein (GFAP).

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Mixossarcoma em mesentério de cão

Cited by 4 publications

References 3 publications

I Simpósio de Ciência Animal e II Fórum de Veterinária e Zootecnia do IF Goiano

I Simpósio de Ciência Animal e II Fórum de Veterinária e Zootecnia do IF Goiano

Radiographic, Citomorphological, and Histochemical Characterization of the Skin Mixosarcoma in a Bitch

Cutaneous myxosarcoma in a Syrian hamster (Mesocricetus auratus)

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