1999
DOI: 10.1590/s0102-09351999000300005
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Abstract: Realizou-se uma intoxicação experimental em bovinos, pela administração oral, com diferentes doses de toxina botulínica tipo D. O objetivo foi determinar o tempo de permanência da toxina no sangue circulante de bovinos, pela detecção da toxina no soro mediante bioensaio em camundongos, e de verificar a presença da toxina no fígado, no baço, nos rins e no coração, e no conteúdo ruminal de bovinos que morreram e/ou foram sacrificados. Utilizaram-se 12 bovinos, mestiços, divididos em quatro grupos de três animais… Show more

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Cited by 3 publications
(3 citation statements)
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“…The morbidity coefficient was 0.39% (25/6300) and the lethality coefficient was 100%. It is important to emphasize that the morbidity and lethality coefficients involving botulism outbreaks are highly variable, since the impacts caused by this disease depend on many factors such as the amount, concentration, and period of ingestion of the neurotoxin consumed by the animals (Colbachini et al 1999). In other botulism outbreaks in confined animals, the morbidity rate was varied: for example, in animals infected with corn silage, a 6.81% rate was observed; while in another study evaluating 1,087 animals confirmed to be at-risk who were receiving contaminated maize, the average coefficient morbidity was close to 29.34% (Dutra 2001); and in confined animals receiving poultry litter, the variation in morbidity was from 3.43% to 100% (Dutra et al 2005).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The morbidity coefficient was 0.39% (25/6300) and the lethality coefficient was 100%. It is important to emphasize that the morbidity and lethality coefficients involving botulism outbreaks are highly variable, since the impacts caused by this disease depend on many factors such as the amount, concentration, and period of ingestion of the neurotoxin consumed by the animals (Colbachini et al 1999). In other botulism outbreaks in confined animals, the morbidity rate was varied: for example, in animals infected with corn silage, a 6.81% rate was observed; while in another study evaluating 1,087 animals confirmed to be at-risk who were receiving contaminated maize, the average coefficient morbidity was close to 29.34% (Dutra 2001); and in confined animals receiving poultry litter, the variation in morbidity was from 3.43% to 100% (Dutra et al 2005).…”
Section: Discussionmentioning
confidence: 99%
“…Botulism is a disease that impacts humans and animals alike, affecting the muscles of locomotion, chewing, swallowing, and breathing, and ultimately resulting in a progression to flaccid paralysis and respiratory arrest (Kriek & Ondendaal 1994, Hogg et al 2008, Maréchal et al 2016. It is considered a non-febrile and highly fatal intoxication, usually caused by the ingestion of botulinum toxins present in decomposing organic matter, which is usually of animal origin but can also be present in vegetable matter (Colbachini et al 1999, Tavella et al 2014.…”
Section: Introductionmentioning
confidence: 99%
“…Despite this, botulism outbreaks associated with contaminated feed increases proportionally matters, becoming responsible for most reports from the 1990s (LOBATO et al, 2008). Sources of Botulism outbreaks commonly reported over the past two decades include food supplements, poorly packaged silage or silage contaminated with small animal carcasses (cats, rodents and birds), and poultry litter, one of the main causes of outbreaks to date (SCHOCKEN-ITURRINO & AVILA, 1991;ORTOLANI et al, 1997;LEMOS, 2005;DUTRA et al, 2005;LOBATO et al, 2008;COSTA et al, 2008;CÂMARA et al, 2011;RIBAS et al, 2013;CÂMARA et al, 2014;RAYMUNDO et al, 2014). Use of poultry litter in ruminant feeding was prohibited in 2004 due to the risk of bovine spongiform encephalopathy (BSE) (BRASIL, 2009), but it is still commonly used in cattle farming in Brazil, especially in dairy farms in the southeast and south of the country.…”
Section: Botulism In Cattle and Other Domestic Ruminantsmentioning
confidence: 99%