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Cited by 8 publications
(5 citation statements)
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References 56 publications
(63 reference statements)
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“…Acute Lymphoblastic Leukemia (ALL) is a lymphoid progenitor cells malignancy and the most common type of cancer in children (Tomizawa & Kiyokawa, 2017). MicroRNAs have been con rmed to play a signi cant role in regulation of hematopoiesis (Slavov, Gimenes Teixeira, & Rego, 2010). Several microRNAs have been found to be up-or down-regulated in patients with ALL (Calin, et al, 2004;Garzon, et al, 2008;Luan, Yang, & Chen, 2015;Wallaert, et al, 2017).…”
Section: Discussionmentioning
confidence: 99%
“…Acute Lymphoblastic Leukemia (ALL) is a lymphoid progenitor cells malignancy and the most common type of cancer in children (Tomizawa & Kiyokawa, 2017). MicroRNAs have been con rmed to play a signi cant role in regulation of hematopoiesis (Slavov, Gimenes Teixeira, & Rego, 2010). Several microRNAs have been found to be up-or down-regulated in patients with ALL (Calin, et al, 2004;Garzon, et al, 2008;Luan, Yang, & Chen, 2015;Wallaert, et al, 2017).…”
Section: Discussionmentioning
confidence: 99%
“…Recent data show the role of miR‐155 in the differentiation of T‐cells into different effectors T‐helper (Th) cell subsets. miR‐155 regulates the differentiation of T‐cells into Th type 1 cells, and its absence results in the direct differentiation from T‐cells to Th type 2 cells (O'Connell et al, ; Slavov et al, ; Seddiki, Brezar, Ruffin, Levy, & Swaminathan, ; Thai et al, ; Zhang et al, ).…”
Section: Involvement Of Mirnas In Lymphopoietic Processmentioning
confidence: 99%
“…Nonetheless, their development and activation at the periphery are controlled by complex protein signaling pathways, which are regulated by the miRNAs (Johanson et al, 2014;Slavov, Teixeira, & Rego, 2010). Several research groups described miRNA expression profile and/or function during the normal (and malignant) hematopoiesis in mouse and humans (Hu & Li, 2016) suggesting that miRNAs are pivotal regulators of hematopoiesis implicated in regulating both the maintenance of the "stemness" of the early progenitors and the various stages of differentiation to mature cells.…”
Section: Involvement Of Mirnas In Lymphopoietic Processmentioning
confidence: 99%
“…Nonetheless, their development and activation at the periphery are controlled by complex protein signaling pathways, which are regulated by the miRNAs. 33 35 …”
Section: The Function Of Mirnas In Normal Lymphopoiesismentioning
confidence: 99%
“…miRNA-155 regulates the differentiation of T-cells into Th type 1 cells, and its absence results in the direct differentiation from T-cells to Th type 2 cells. 33 , 34 , 42 44 …”
Section: The Function Of Mirnas In Normal Lymphopoiesismentioning
confidence: 99%