Treadmill exercise testing of asymptomatic men and women without evidence of heart disease

Chalela, W.A.; Fukushima, R.B.; Araujo, F.; Lima, A.C.P.; Moffa, P.J.; Mansur, A.J.

doi:10.1590/s0100-879x2009007500005

Cited by 1 publication

(1 citation statement)

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“…Cardiovascular performance during aerobic exercise and peripheral vasodilator capacity has been demonstrated to be influenced by age [1,2,3,4],gender [5,6,7],body mass index, andphysical fitness [8,9]. Good performance during exercise, including favorable responses for heart rate, blood pressure and functional capacity, has been associated with cardiovascular health [10,11,12].…”

Section: Introductionmentioning

confidence: 99%

Exercise-Induced Muscle Vasodilatation and Treadmill Exercise Test Responses in Individuals without Overt Heart Disease

Nunes¹,

Giampaoli²,

Freitas³

et al. 2013

Cardiology

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Background: The beneficial effects of exercise on cardiovascular health may be related to the improvement in several physiologic pathways, including peripheral vascular function. The aim of this study was to evaluate the relationship between cardiovascular responses during the treadmill exercise test and exercise-induced muscle vasodilatation in individuals without overt heart disease. Methods: The study included 796 asymptomatic subjects (431 females and 365 males) without overt heart disease. We evaluated the heart rate (chronotropic reserve and heart rate recovery), blood pressure (maximum systolic and diastolic blood pressure as well as systolic blood pressure recovery) and exercise capacity during symptom-limited treadmill exercise testing. Exercise-induced muscle vasodilatation was studied with venous occlusion plethysmography and estimated by forearm blood flow and vascular conductance responses during a 3-min handgrip maneuver. Results: Forearm blood flow increase during the handgrip exercise was positively associated with heart rate recovery during treadmill exercise testing (p < 0.001). Forearm vascular conductance increase during the handgrip exercise was inversely associated with exercise diastolic blood pressure during exercise treadmill testing (p = 0.038). No significant association was found between exercise capacity and exercise-induced muscle vasodilation. Conclusion: In a sample of individuals without overt heart disease, exercise-induced muscle vasodilatation was associated with heart rate and blood pressure responses during treadmill exercise testing, but was not associated with exercise capacity. These findings suggest that favorable hemodynamic and chronotropic responses are associated with better vasodilator capacity, but exercise capacity does not predict muscle vasodilatation.

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