Flow rate, pH and calcium concentration of saliva of children and adolescents with type 1 diabetes mellitus

Abstract

9%), with means ± SD unstimulated salivary flow rate of 0.15 ± 0.1 mL/min compared to 0.36 ± 0.2 mL/min for group B (P < 0.01). Stimulated salivary flow rate was similar by both groups and above 2.0 mL/min. Saliva pH was 6.0 ± 0.8 for group A and significantly different from 7.0 ± 0.6 for group B (P < 0.01). Salivary calcium was 14.7 ± 8.1 mg/L for group A and significantly higher than 9.9 ± 6.4 mg/L for group B (P < 0.01). Except for elevated calcium concentrations in saliva, salivary parameters favoring caries such as low saliva pH and unstimulated salivary flow rate were observed in T1DM individuals.]]>

Oral health and characteristics of saliva in diabetic and healthy children

“…DMF in our patients was higher than control group, in other word the average number of decayed, missing or restored teeth are more than healthy people. These findings are compatible with studies of Moriera, 13 Ben Arieh, 1 During statistical analysis we achieved the correlation between salivary parameters and DMF and MGI. In the patients group there was a negative correlation between salivary pH DMF and a positive correlation between the TAC and saliva flow rate.…”

“…1,13 In this study same as Moreira study, 1 pH of saliva in diabetic patients was less than healthy individuals and had acidic nature.…”

“…2 The risk of tooth decay in patients with diabetes is significantly greater than the controls that is because of reducing the ability of saliva in cleaning, neutralizing and antimicrobial activity. Moriera et al 1 in a study showed that the rate of nonstimulated salivary secretion and salivary pH is lower in children with diabetes in comparison to healthy children.…”

Impact of Hyperglycemia on Xerostomia and Salivary Composition and Flow Rate of Adolescents with Type 1 Diabetes Mellitus

“…Moreover, amylase salivary concentration in adolescents with DM1 did not show significant differences compared with controls. Previous studies (Twetman et al, 2002;Mata et al, 2004;Carda et al, 2006;Moreira et al, 2009) have shown significant differences in total proteins salivary concentrations between subjects with and without DM1. Others studies are needed to further investigate the association of hypoglycemia with total proteins salivary concentrations in adolescents with DM1.…”

“…Some studies (Belazi et al, 1998;López et al, 2003;Moreira et al, 2009) have shown this difference, whereas others studies (Swanljung et al, 1992;Carda et al, 2006) have not found difference in glucose salivary concentrations between subjects with and without DM1. The increased concentrations of glucose in the saliva of adolescents with DM1 may be important for controlling and monitoring the disease.…”