2008
DOI: 10.1590/s0100-879x2008001000017
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Abstract: 27), quality of sleep by the Pittsburgh Sleep Quality Index (PSQI >6), excessive daytime sleepiness by the Epworth Sleepiness Scale (ESS >10) and clinical disability by the Expanded Disability Status Scale (EDSS). Forty-four patients (32 women) aged 14 to 64 years (43 ± 14) with disease from 0.4 to 23 years (6.7 ± 5.9) were evaluated. Thirty-five were classified as relapsing-remitting, 5 as primary progressive and 4 as secondary progressive. EDSS varied from 0 to 8.0 (3.6 ± 2.0). RLS was detected in 12 cases (… Show more

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Cited by 96 publications
(84 citation statements)
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“…The association of RLS and multiple sclerosis (MS) has been so consistent that it has recently been suggested that MS should be another recognized secondary cause for RLS 2 . During the last decade, a few studies [2][3][4][5][6] have suggested that the association of these two neurological conditions seems to be more than fortuitous. However, not all authors have agreed with this hypothesis 7 , which left the matter still open to discussion.…”
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confidence: 99%
“…The association of RLS and multiple sclerosis (MS) has been so consistent that it has recently been suggested that MS should be another recognized secondary cause for RLS 2 . During the last decade, a few studies [2][3][4][5][6] have suggested that the association of these two neurological conditions seems to be more than fortuitous. However, not all authors have agreed with this hypothesis 7 , which left the matter still open to discussion.…”
mentioning
confidence: 99%
“…Among the patients with MS, 71 (78%) had relapsingremitting MS (RRMS), 8 (8.8%) had secondary progressive MS (SPMS), 3 (3.3%) had progressive relapsing MS (PRMS), and 9 (9.9%) had primary progressive MS (PPMS). The median number of attacks was 3 (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20) and the median EDSS score was 3 (0-9) in the MS group (Table 1).…”
Section: Resultsmentioning
confidence: 99%
“…RLS symptoms appear usually after the onset of MS (18)(19)(20)23,26,27). There is no relationship between MS subtypes and the presence of RLS (18,20,(22)(23)(24)(25)31). There are only three studies that investigated the relationship between functional system involvement and the presence of RLS in MS patients (19,23,25).…”
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confidence: 99%
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“…Families MS results in many physical, 12 cognitive, 13 economic, 14 psychosocial, 10 and emotional 15 setbacks that inevitably transform the lives of affected patients as well as their families. Physical problems include chronic pain, 16 decreased mobility, 17 fatigue or weakness, 18,19 bowel dysfunction, 20 and sexual dysfunction. 21 Examples of cognitive deficits include memory problems, 22 language comprehension and fluency problems, 23 and attention deficits.…”
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confidence: 99%