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Cited by 4 publications
(7 citation statements)
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“…Except for the initial study that identified a significant association between the presence of the ApoE e2 allele (vs. the e3 allele) and hypertension (OR¼1.76; 95% CI, 1.16 to 2.68), other studies failed to show this trend with ORs leftward approaching the unity. The association between the e4 allele (vs. the e3 allele) and hypertension remained significant for all other studies except for the initial study 18 and another study 23 conducted in Brazilians. The findings were especially significant in a study conducted in Chinese individuals (OR¼4.14, 95% CI, 2.63 to 6.52).…”
Section: Meta-analysis Resultsmentioning
confidence: 77%
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“…Except for the initial study that identified a significant association between the presence of the ApoE e2 allele (vs. the e3 allele) and hypertension (OR¼1.76; 95% CI, 1.16 to 2.68), other studies failed to show this trend with ORs leftward approaching the unity. The association between the e4 allele (vs. the e3 allele) and hypertension remained significant for all other studies except for the initial study 18 and another study 23 conducted in Brazilians. The findings were especially significant in a study conducted in Chinese individuals (OR¼4.14, 95% CI, 2.63 to 6.52).…”
Section: Meta-analysis Resultsmentioning
confidence: 77%
“…As shown in Table 2, no individual study had an undue influence on the summary ORs for comparing e2 vs. e3 or E2/2 and E2/3 vs. E3/3 with regard to the association of each allele and hypertension. However, with regard to the comparison of the e4 allele vs. the e3 allele and the risk of hypertension, the results of the analysis were quite different when the initial 18 and final study 23 were excluded from the analysis. When each of these studies was excluded, the ORs obtained were 2.13 (95% CI, 1.05 to 4.33) and 2.12 (95% CI, 1.07 to 4.20), respectively, with both reaching statistical significance.…”
Section: Sensitivity Analysesmentioning
confidence: 97%
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“…További öt felmérés arra az eredményre jutott, hogy az e2-nek védő szerepe van a cardiovascularis betegségekkel szemben, vagy nem mutat velük összefüggést [35,44,45,46,47,48…”
Section: Apoe4unclassified