2008
DOI: 10.1590/s0100-879x2008000600008
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Abstract: The objective of the present study was to determine the acute effect of hemodialysis on endothelial venous function and oxidative stress. We studied 9 patients with end-stage renal disease (ESRD), 36.8 ± 3.0 years old, arterial pressure 133.8 ± 6.8/80.0 ± 5.0 mmHg, time on dialysis 55.0 ± 16.6 months, immediately before and after a hemodialysis session, and 10 healthy controls matched for age and gender. Endothelial function was assessed by the dorsal hand vein technique using graded local infusion of acetylch… Show more

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Cited by 10 publications
(7 citation statements)
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“…These findings are opposite to data presented by Silva et al [18], who reported that the process of hemodialysis reduced oxidative stress and improved venous endothelial function as reflected by the improved endotheliumdependent venodilation test. In another clinical studies, hemodialysis-induced oxidative stress and endothelial dysfunction were described [19,20].…”
Section: Discussioncontrasting
confidence: 99%
“…These findings are opposite to data presented by Silva et al [18], who reported that the process of hemodialysis reduced oxidative stress and improved venous endothelial function as reflected by the improved endotheliumdependent venodilation test. In another clinical studies, hemodialysis-induced oxidative stress and endothelial dysfunction were described [19,20].…”
Section: Discussioncontrasting
confidence: 99%
“…On the other hand, due to the high turbulence of blood at the needle site, lack of biocompatibility of dialysis membranes, and dialysate problems, as well as hemodynamic changes, HD itself might directly or indirectly damage the vascular endothelium and thereby weaken the beneficial effect of HD on endothelial functions. At present, reports about the effects of HD on endothelial functions are not consistent . In this study, we compared pre‐dialysis plasma vasoactive substances with their post‐dialysis levels in both IDH MHD patients and non‐IHD MHD patients, focusing on the renin–angiotensin–aldosterone (ALD) system (RAAS), sympathetic nervous system (SNS) activity, as well as NO, ET‐1, and N‐terminal fragment brain natriuretic peptide (NT‐proBNP) activities, in order to gain insight into the role of vasoactive substances in the development of IDH.…”
Section: Introductionmentioning
confidence: 99%
“…At present, reports about the effects of HD on endothelial functions are not consistent. [14][15][16][17] In this study, we compared pre-dialysis plasma vasoactive substances with their post-dialysis levels in both IDH MHD patients and non-IHD MHD patients, focusing on the renin-angiotensin-aldosterone (ALD) system (RAAS), sympathetic nervous system (SNS) activity, as well as NO, ET-1, and N-terminal fragment brain natriuretic peptide (NT-proBNP) activities, in order to gain insight into the role of vasoactive substances in the development of IDH.…”
Section: Introductionmentioning
confidence: 99%
“…Venous endothelial function was assessed in all patients via the dorsal hand vein technique, 11 a method for which our group has published details elsewhere 10,12,13. Briefly, a 23-gauge butterfly needle was inserted into a suitable vein on the back of the hand, and a continuous infusion of physiologic saline solution (0.3 mL/min) was started.…”
Section: Methodsmentioning
confidence: 99%