1997
DOI: 10.1590/s0100-84551997000100018
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Abstract: Interphase cytogenetics, utilizing fluorescence in situ hybridization (FISH) techniques, has been successfully applied to diffuse and solid tissue specimens. Most studies have been performed on isolated cells, such as blood or bone marrow cells; a few have been performed on cells from body fluids, such as amniotic fluid, urine, sperm, and sputum. Mechanically or chemically disaggregated cells from solid tissues have also been used as single cell suspensions for FISH. Additionally, intact organized tissue sampl… Show more

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Cited by 11 publications
(7 citation statements)
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“…12 In contrast, interphase cytogenetics using fluorescence in situ hybridization (FISH) probes specific for individual chromosomes or loci circumvents some of these shortcomings and allows for a rapid and comprehensive characterization of chromosome alterations present in a tumor. 13…”
mentioning
confidence: 99%
“…12 In contrast, interphase cytogenetics using fluorescence in situ hybridization (FISH) probes specific for individual chromosomes or loci circumvents some of these shortcomings and allows for a rapid and comprehensive characterization of chromosome alterations present in a tumor. 13…”
mentioning
confidence: 99%
“…[9][10] when the mitotic index is low, or the cytogenetics preparation is suboptimal, an accurate chromosomal profile cannot be achieved using standard banding techniques. [11] FISH results of CEP 3 in the present study showed the frequent gains of chromosome 3 in squamous cell carcinoma over the chromosome 17 FISH technique was also carried out in 10 healthy samples (control) to make a comparison between the diseased condition and the normal samples.…”
Section: Resultsmentioning
confidence: 99%
“…Fluorescence in situ hybridization (FISH) is an indispensable technique in the study of the physical mapping of human genome because it allows a precise regional chromosomal location of single copy genes or repeated sequences of DNA. It can be used in paraffin-embedded samples, analyzes the ploidy and identifies the most common chromosomal abnormalities related to NM abortions according to the probes were used [12,19]. Molecular genotyping of microsatellites has been widely used in distinguishing HM.…”
Section: Journal Of Gynecology and Women's Healthmentioning
confidence: 99%