Efeitos da corticoterapia materna nos valores hemogasométricos de cordeiros nascidos a termo e prematuros

Feitosa, Francisco Leydson Formiga; Ávila, Larissa Gabriela; Bovino, Fernanda; Santos, Guilherme Gonçalves Fabretti; Mendes, Luiz Cláudio Nogueira; Peiró, Juliana Regina; Perri, S. H. V.

doi:10.1590/s0100-736x2017000500016

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…The vital signs heart rate (HR), respiratory rate (RR) and rectal temperature (RT), which are associated with the capillary refill time (CRT) and eye mucous membrane color of the lambs, were assessed immediately after birth (T 0 ), at 15 minutes (T 1/4 ) and at one hour (T 1 ), six hours (T 6 ), 12 hours (T 12 ), 24 hours (T 24 ) and 48 hours after birth (T 48 ). The vitality assessment was performed using the Activity, Pulse, Grimace, Appearance, Respiration (APGAR) score at T 0 and T 1/4 (Feitosa and Benesi, 2014).…”

Section: Methodsmentioning

confidence: 99%

Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section

Bovino

Denadai

Ávila

et al. 2019

Arq. Bras. Med. Vet. Zootec.

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The aim of this study was to assess the vitality and lung function of preterm lambs. Twenty seven preterm lambs were divided in four groups. Group I (n=6) preterm lambs/ control; group II (n=9) lambs born to mothers that were treated with dexamethasone antepartum; group III (n=6) lambs treated with surfactant; and group IV (n=6) lambs treated with surfactant and born to mothers that were treated with dexamethasone antepartum. The APGAR score was performed after birth (T0) and 15 minutes later (T1/4) to assess vitality. The vital signs, blood gas analysis, spirometry and capnometry were assessed immediately after birth and continued until 48 hours. Chest radiographs were performed at T0, T24 and T48. Significant rectal temperature interactions occurred at T1 and T6 depending on the type of treatment used. All animals showed low pH values, which were associated with high pCO2 values and HCO3 -values that increased over time from immediately after birth to two days of age. Higher tidal volume values were observed at T1/4, T1 and T24 when the animals were not treated with surfactant. Capnometry showed significant interactions between treatments at T0. Premature animals showed low vitality and impaired pulmonary function.

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Section: Methodsmentioning

confidence: 99%

Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section

Bovino

Denadai

Ávila

et al. 2019

Arq. Bras. Med. Vet. Zootec.

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“…In other words, lambs born just 7 days before the expected date of delivery are at great risk of dying, even before the first 24 hours of life. Therefore, according the some studies, lambs born with an average of 138 days can be considered premature (Radostits et al 2007, Avila et al 2014, Bovino 2015, Feitosa et al 2017, Miura et al 2019.…”

Section: Introductionmentioning

confidence: 99%

Assessment of fetal lung maturity using analysis of amniotic fluid from ewes that gave birth prematurely and at term

Souza

Bovino²,

Avilla

et al. 2020

Pesq. Vet. Bras.

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The aim of this study was to evaluate the lung maturity of premature and full-term lambs by analyzing amniotic fluid using the following methods: Clements test, Nile blue cytology test, hematoxylin-Shorr stain, lamellar body count, and radiographic tests. The use of these methods is intended to identify high-risk newborns and provide immediate clinical intervention after birth. Altogether, 56 animals (24 ewes and 32 lambs) were included in the study and divided into 3 groups. Group I consisted of 8 ewes that were at approximately 145 days of gestation; this group delivered 10 lambs naturally. Group II consisted of 8 ewes that were at 138 days’ gestation; this group delivered 11 lambs by cesarean section. Group III consisted of 8 ewes at 138 days’ gestation; this group was administered intramuscular dexamethasone (16mg/animal) 36 hours prior to a cesarean section. Group III delivered11 lambs. Cytological tests were performed using a microscope with a maximum magnification of 1000x, while the Clements test was visually observed by one of the researchers. Amnioticfluid lamellar body counts were measured using transmission electron microscopy. Among the staining methods, hematoxylin-Shorr was reliable, and Group III had a greater number of orangeophilic cells when compared to Group II, probably due to corticoid administration. The Clements test showed pulmonary maturity in approximately 20% of Group I lambs and Group II showed 9.1% of bubbles; however, Group III had the highest pulmonary maturity percentage (36.4%). The lamellar bodies were measured, and all groups had sizes between 0.019 and 0.590μm. Radiographic evaluation revealed that the majority of lambs presented some level of pulmonary radiodensity, indicating an acinar pattern at birth. These results are in line with the expectations of each group. We found that the normal group showed greater pulmonary maturity, whereas Group II presented pulmonary immaturity, which is expected because this group comprised lambs born prematurely and Group III showed pulmonary maturity almost comparable to the normal delivery group (Group I). This is due to the fact that although these animals are premature, the use of dexamethasone helped in pulmonary maturation. Therefore, these pulmonary maturity tests are considered effective when more than one technique is used and can be used routinely in the care of a pregnant ewe in labor, where a simple collection of amniotic fluid can predict a high-risk pregnancy and alert the veterinarian if the newborn needs intensive supportive treatment.

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Impact of different dexamethasone treatment protocols in goats for preterm neonatal outcomes

Narciso

Alcindo

Bovino³

et al. 2022

Small Ruminant Research

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Efeitos da corticoterapia materna nos valores hemogasométricos de cordeiros nascidos a termo e prematuros

Cited by 4 publications

References 13 publications

Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section

Influence of dexamethasone and surfactant in the vitality and lung function of preterm lambs born by cesarean section

Assessment of fetal lung maturity using analysis of amniotic fluid from ewes that gave birth prematurely and at term

Impact of different dexamethasone treatment protocols in goats for preterm neonatal outcomes

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