Histological features of the placenta and their relation to the gross and data from Thoroughbred mares

Abstract

RESUMO.-[Achados histológicos da placenta e sua relação com seus aspectos macroscópicas e dados de éguas Puro Sangue Inglês.] A placenta é um órgão transitório originado do tecido fetal e materno, com função de transportar nutrientes da mãe para o feto. O objetivo deste estudo foi descrever os achados histológicos das placentas de éguas Puro Sangue Inglês (PSI) a termo e avaliar sua relação com a macroscopia da placenta e dados dessas éguas. O estudo utilizou 188 éguas PSI. Foram realizadas observações clinicas diárias para presença de sinais clínicos de placentite e ultrassonografia mensal para avaliar saúde do feto e placenta. As éguas que apresentaram sinais clínicos de placentite durante a gestação foram tratadas. Os partos foram assistidos, as placentas avaliadas macroscopicamente e coletadas imediatamente após sua expulsão. Como dados das éguas foram considerados: idade, tempo de gestação, número de partos, tempo de eliminação da placenta, comprimento de cordão umbilical, peso da placenta e sinais clínicos de placentite. A avaliação histológica das placentas demonstrou extensiva vacuolização citoplasmática das cé-lulas do epitélio coriônico das regiões areolares, presença de infiltrados inflamatórios e hipoplasia-atrofia de microcotilédones. A maior parte dos achados macroscópicos da placenta foram condizentes com os resultados de histolo- The placenta is a transitory organ that originates from maternal and fetal tissues, the function of which is transporting nutrients from the mother to the fetus. The aim of this study was describe the histological features of placentas in healthy Thoroughbred mares at foaling and evaluate their relation with the gross placental and data of these mares. For this study 188 Thoroughbred mares were used. It was performed clinical observation for signs of placentitis during daily health checks and ultrasonic examination monthly to assess the fetus and placenta. All of the mares that exhibited clinical signs of placentitis were treated during gestation. The parturition was assisted, the placentas were grossly evaluated and samples were collected immediately after expulsion. The following data were considered for each mare: age, gestational age, number of parturition, time for placental expulsion, umbilical-cord length, placental weight and clinical signs of placentitis. Histological evaluation of the placentas revealed extensive cytoplasmic vacuolization of the epithelial areolar cells, presence of inflammatory infiltrates and hypoplasia-atrophy of the microcotyledons. Most of the gross placental findings were consistent with the histological results. In conclusion the mares with a vacuolated placental chorionic epithelium were older and had experienced a larger number of births. Great part of the mares with inflammatory infiltrates did not showed any clinical signs of placentitis during gestation.

Pregnancy loss due to amnionitis in anglo‐arabian mare—Case report

“…The inflammatory process may be related to the decreased vascularization and consequently to placental insufficiency, emphasizing the importance of ultrasound monitoring in equine pregnancy. The combined utero‐placental thickness assessed by the transrectal ultrasound is the most common tool for diagnosis of placental insufficiency in gestational follow‐up (Campos, Souza, Pinna, & Ferreira, ); however, the definitive diagnosis of placental disorders that are not obvious during pregnancy requires histopathological examination (Pazinato et al, ).…”

Comparison of gross morphological and histological features of placenta between hypertensive and normotensive pregnant women attending Muhimbili National Hospital.

“…The placenta is the vital fetomaternal organ that is responsible for the maintenance of the pregnancy and promotion of fetal growth and development (Communication, 2017). It connects the fetus to the uterine wall thus providing nutrients and oxygen to the fetus, eliminating waste products from the fetus; working as the digestive system, lung and kidney respectively (Pazinato et al, 2016). The optimal survival, growth and development of the fetus are correspondence to the appropriate formation and development of the placenta (Wang and Zhao, 2010).…”