Avaliação dos fatores etários sobre a função renal de ovelhas Santa Inês

Abstract

RESUMO.-Este estudo avaliou a função renal de fêmeas ovinas hígidas da raça Santa Inês, criadas no Estado de São Paulo, com o objetivo de estabelecer valores de referência, além de determinar possíveis variações dos valores de seus parâmetros causados por fatores etários. Foram determinados os valores de ureia, creatinina, sódio e potássio séricos e urinários, e os valores de GGT urinário de 128 animais, divididos em 4 grupos de acordo com a idade. Foi realizada, também a urinálise das 128 amostras de urina. Não foi observada diferença significativa dos valores de densidade entre todos os grupos. Entretanto, constatou-se aumento de valores de ureia, creatinina, sódio e diminuição de proteínas e GGT urinários nos grupos 2, 3 e 4 que eram mais velhos do que o grupo 1. Em relação aos parâmetros séricos, observou-se diferença significativa dos valores de ureia e creatinina entre os grupos, pois uréia e creatinina aumentaram e potássio diminuiu nos animais do grupo 2, 3 e 4 que eram mais velhos. Avaliando-se os resultados obtidos para os exames da função renal, verificou-se que os valores médios na urina da densidade foi de 1,03±0,01; pH 7,71±1,35; ureia em mg/dL foi 1342±1085; de creatinina 42,39±23,36; de proteínas totais em g/dL foi de 5,61±2,88; GGT em U/L foi de 1,44±1,31; sódio e potássio em mmol/L foi de 15,93±20 This study evaluated kidney function of healthy Santa Inês ewes, bred in São Paulo State. The aim of this paper was to establish standard reference values and stipulate value variation caused by age group factor. We determined seric and urinary levels of urea, creatinine, sodium and potassium, and urinary GGT from 128 ewes, divided into 4 groups according to age. Also urinalysis was made in 128 urine samples. No significant statistical difference was found regarding density values between all groups, although there was an increase in urea values, creatinine and sodium, and an decrease in urinary proteins and GGT in group 2, 3 and 4 older than group1. In relation to the seric parameters, there was significative statistical difference in urea and creatinine values between the groups, as an increase in urea and creatinine. Potassium decreased in the older groups 2, 3 and 4. Evaluating the results obtained for renal function, we found that the mean values of density were 1.03±0.01, pH 7.1±1.35, urea (mg/dL) 1342±1085, creatinin 42.39±23,36, total protein (g/dL) 5.61±2.88, GGT (U/L) 1.44±1.31, sodium and potassium (mmol/L) were 15.93±20.13 and 240±117 respectively. In the serum medium values were: urea (mg/dL) 32.33±19.81, creatinine 1.22±0.20, sodium and potassium (mmol/L) 145.7±8.8 and 5.5±1.30 respectively.

Crude glycerin inclusion in Santa Inês ewes’ diet before and during the breeding season: its effects on physiological parameters, hematological variables, and reproductive performance

“…Urea is an indicator of protein metabolism and its concentration in the blood has been used to monitor dietary protein. Again, the age factor is most likely responsible for the differences observed in the blood concentrations of the indicators, as in nulliparous ewes the development process promotes higher protein use metabolism, consequently causing a decrease of nitrogen compounds (Henriques, Gregory, Rizzo, Hasegawa, & Meira, 2016). (2008).…”

Influence of breed on the clinical and hemato-biochemical parameters in sheep experimentally infected with Leptospira sp.

“…As the Santa Inês and crossbred sheep presented some particularities in the normal hemato-biochemical standards, the reference values were compared to those previously determined (Henriques et al., 2016; Rabassa et al., 2009; Salviano et al., 2013; Lima et al., 2015). Urea and creatinine concentration; serum activity of the aspartate aminotransferase (AST); gamaglutamiltransferase (GGT); total protein and albumin; total, direct and indirect bilirubin were analyzed spectrophotometrically using commercial kinetic and colorimetric tests available for the automated biochemical analyzer (Labtest, Labtest Diagnostica S.A.®, Minas Gerais, Brazil) in a biochemical analyzer (Cobas c111 Analyzer, Roche Diagnostics®, Risch-Rotkreuz, Switzerland).…”

Metabolic profile and renal function of lambs fed with maniçoba hay replacement by spineless cactus

“…Few scientific investigations on the renal function of sheep submitted to diets with spineless cactus were found in the literature (VIEIRA et al, 2008b;PORDEUS NETO et al, 2016), confirming the need for further studies on the subject matter. According to HENRIQUES et al (2016), the study of renal function is relevant, mainly in the ovine species, due to the high incidence of diseases in the urinary system.…”