2008
DOI: 10.1590/s0100-736x2008000600009
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Abstract: RESUMO.-[Lesões entéricas em suínos afetados por síndrome multissistêmica do definhamento dos suínos.]Amostras de linfonodos mesentéricos e intestinos de 79 leitões desmamados refugos, entre 3 e 5 meses de idade e confirmados como naturalmente afetados pela síndrome multissistêmica do definhamento foram estudadas. Os suí-nos eram oriundos de 12 criações no sul do país e foram selecionados em função dos sinais clínicos e/ou lesões macroscópicas sugestivos de doença entérica. Infiltrados linfoistiocíticos de int… Show more

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Cited by 13 publications
(14 citation statements)
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“…In intestinal tissues PCV2 is found in Peyer's patches associated with lymphoid depletion and hystiocytic replacement in the follicular centers as well in enterocytes and vascular endothelial cells (Segalés et al 2004, Zlotowski et al 2008. Also, depletion of goblet cells in the large intestine of PCV2-affected pigs has been reported, suggesting that the virus may interfere with the intestinal defense system via more than one mechanism (Zlotowski et al 2008).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In intestinal tissues PCV2 is found in Peyer's patches associated with lymphoid depletion and hystiocytic replacement in the follicular centers as well in enterocytes and vascular endothelial cells (Segalés et al 2004, Zlotowski et al 2008. Also, depletion of goblet cells in the large intestine of PCV2-affected pigs has been reported, suggesting that the virus may interfere with the intestinal defense system via more than one mechanism (Zlotowski et al 2008).…”
Section: Discussionmentioning
confidence: 99%
“…Also, depletion of goblet cells in the large intestine of PCV2-affected pigs has been reported, suggesting that the virus may interfere with the intestinal defense system via more than one mechanism (Zlotowski et al 2008). Although the exact mechanism of interaction between Salmonella and PCV2 has not been defined, the presence of PCV2 in a herd may decrease the dose of the bacteria necessary to cause disease and increase the shedding by carrier pigs, probably because of the lymphoid depletion and the disruption of the intestinal defense system caused by the virus infection.…”
Section: Discussionmentioning
confidence: 99%
“…Newborn piglets are susceptible to infection by several enteric microorganisms, including bacteria (enterotoxigenic Escherichia coli and Clostridium perfringens type C), protozoans (Cryptosporidium spp and Isospora suis), and viruses (rotavirus, coronavirus, and calicivirus) , Zlotowski et al 2008, Jeong et al 2009, Linares et al 2009, Médici et al 2011, Marthaler et al 2012.…”
Section: Introductionmentioning
confidence: 99%
“…Porcine group A rotavirus (PoRVA) infections are most frequently identified in episodes of diarrhea in piglets worldwide, including in Brazil (Linares et al 2009, Halaihel et al 2010, Médici et al 2011, Lorenzetti et al 2011; however, the involvement of porcine rotavirus groups B and C (PoRVB and PoRVC) in weaning and post-weaning piglets with diarrhea has also been reported mainly in transversal epidemiological studies (Magar et al 1991, Zlotowski et al 2008, Médici et al 2010a, 2010b, Médici et al 2011, Marthaler et al 2012.…”
Section: Introductionmentioning
confidence: 99%
“…Studies have revealed that Brazilian pig herds are commonly infected with economically important viruses, including porcine rotavirus groups A, B and C; hepatitis E virus; Aichivirus C; porcine norovirus; porcine enteric picornaviruses; porcine parvovirus; porcine circovirus type 2 and torque teno sus virus, some of which lead to public health concerns (Pescador et al 2007;Barry et al 2008b;Zlotowski et al 2008;Cunha et al 2010;Lorenzetti et al 2011;Médici et al 2011;Gardinali et al 2012;Ritterbusch et al 2012;de Arruda Leme et al 2013Ribeiro et al 2013;Donin et al 2014;Silva et al 2014;Stipp et al 2014). It is not unusual to find pigs infected with several of these viruses at the same time (Pescador et al 2007;Zlotowski et al 2008;Médici et al 2011;Lorenzetti et al 2011;Donin et al 2014).…”
Section: Discussionmentioning
confidence: 99%