2007
DOI: 10.1590/s0100-736x2007000300004
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Histopathological changes in liver and gill epithelium of Nile tilapia, Oreochromis niloticus, exposed to waterborne copper

Abstract: Nile tilapia, Oreochromis niloticus, of both sexes were reared in freshwater and exposed to 0.5, 1.0 and 2.5mg L-1 of waterborne copper for a period of 21 days. Liver and gill samples were collected after 21 days of exposure to copper and lesions were analyzed by light microscopy. The main histopathological changes observed in gills exposed to the highest concentration were edema, lifting of lamellar epithelia and an intense vasodilatation of the lamellar vascular axis. Although less frequent, lamellar fusion … Show more

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Cited by 171 publications
(98 citation statements)
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“…Similar necroses were also found in tilapias exposed to streptozotocine (Wright et al, 1999) and copper (Figueiredo-Fernandes et al, 2007). The presence of focal necroses in the tilapia livers in the present study suggests a toxic nature in the chemical components of these fractions.…”
Section: Effects Of Hexanic Fraction On Hepatopancreassupporting
confidence: 88%
“…Similar necroses were also found in tilapias exposed to streptozotocine (Wright et al, 1999) and copper (Figueiredo-Fernandes et al, 2007). The presence of focal necroses in the tilapia livers in the present study suggests a toxic nature in the chemical components of these fractions.…”
Section: Effects Of Hexanic Fraction On Hepatopancreassupporting
confidence: 88%
“…Neste sentido, indutores de irritação branquial têm sido investigados com muita freqüência, através de análises microscópicas, tais como baixa qualidade da água com pH e temperaturas extremas (Mallatt 1985), agentes tóxi-cos e irritantes como metais pesados e pesticidas (Schwaiger et al 1997, Pane et al 2004, Figueiredo-Fernandes et al 2007, Fontaínhas-Fernandes et al 2008, agentes infecciosos e presença de parasitas (Pavanelli et al 2002).…”
Section: Discussionunclassified
“…Devido a isso, eles podem sofrer alterações morfológicas, o que poderá se refletir como perturbações reversíveis ou irreversíveis à fisiologia destes órgãos. Vários são os estudos que utilizam as brânquias de peixes como bioindicadores de mudanças do meio aquático, visto serem estruturas vitais para a saúde desses animais, pois além de serem o principal local de trocas gasosas, também estão envolvidas nos processos de osmoregulação, equilíbrio ácido-bási-co, excreção de compostos nitrogenados e desempenham ainda a função de órgão sensorial da gustação (Araújo et al 1997, 1999, 2000, Leonardo 1999, Winkaler et al 2001, Lopes 2006, Figueiredo-Fernandes et al 2007, Fontaínhas-Fernandes et al 2008. Qualquer comprometimento nos filamentos e lamelas branquiais, que interfiram em sua função certamente comprometerá a sobrevivência desses animais.…”
Section: Introductionunclassified
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“…Venous blood entered the liver caudally from the intestine via the hepatic portal veins and branches into capillaries known as sinusoids. Sinusoids were lined with reticuloendothelial cells which were in turn surrounded by hepatocytes (Figueiredo-Fernandes et al 2007). However, there were remarkable histological alterations in the liver tissue of the fish from Topolnitsa Dam Lake (Table 4).…”
Section: Histological Alterationsmentioning
confidence: 99%