Leiomiossarcoma de Mama: Relato de caso

Assis, Juliane Oliveira de; Pimentel, A. C.; Filho, Antônio Chambô; Cintra, Luiz Cálice; Scardini, Rolney

doi:10.1590/s0100-72032001000400009

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Leiomyosarcomas grow slowly and may remain asymptomatic for a long period of time, delaying diagnosis and resulting in a worse prognosis [ 8 ]. Diagnosis should be made only after immunohistochemistry study, since conventional methods such as hematoxylin/eosin may fail to differentiate leiomyosarcoma from malignant fibrohistiocytomas [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Retromammary fat, axillary and arm metastases from a retroperitoneal leiomyosarcoma: report of a case with an indolent behaviour

Filho¹,

Melo²,

Alves³

et al. 2017

ecancer

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Leiomyosarcomas are sarcomas that originate within smooth muscle cells and generally occur in older patients. These tumours account for 10% of all soft-tissue sarcomas. Metastases occur most commonly to the lungs, kidneys, and liver. Cutaneous metastases may also occur but are usually a very rare and late event. We present a case of a 46-year-old woman who developed subcutaneous metastasis to the axilla, arm and breast after surgical resection of the primary tumour.The patient maintained controlled disease with surgical resections and clinical follow-up, initiating chemotherapy one year after the diagnosis of metastatic disease.

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Section: Discussionmentioning

confidence: 99%

Retromammary fat, axillary and arm metastases from a retroperitoneal leiomyosarcoma: report of a case with an indolent behaviour

Filho¹,

Melo²,

Alves³

et al. 2017

ecancer

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Primary Leiomyosarcoma of the Breast Papilla: A Case Report

et al. 2020

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Background: Breast leiomyosarcoma is a rare subtype of breast sarcoma, constituting 5–10% of the cases. Less than one-third of reported cases are located in the nipple papillary region, making it an extraordinarily rare malignancy, responsible for less than 0.1% of all malignant breast tumors. As no radiological criteria allow definitive diagnosis of papillary leiomyosarcoma, histopathological and immunohistochemical examination of suspicious lesions is required. The prognosis is generally optimistic compared with those for other breast sarcomas.Case presentation: A 54-year-old previously healthy woman reported the appearance of a nodule in her right nipple in the preceding 9 months, associated with pruritus. Physical examination revealed that the lesion had a cystic consistency and measured approximately 3.0 cm. Imaging examinations showed no involvement of the adjacent breast parenchyma or axillary region and the lesion was classified as Breast Imaging-Reporting and Data System (BI-RADS) category IV. The lesion was excised, and the histopathological diagnosis was well-differentiated leiomyosarcoma of the mammary papilla, with immunohistochemical examination showing positivity for smooth-muscle tissue antigens. A staging CT examination was performed, showing no evidence of distant metastasis. After 2 years of follow-up, the patient shows no sign of tumor recurrence.Conclusion: Although rare, leiomyosarcoma must be included in differential diagnosis of breast masses, especially those involving the periareolar region. Due to its good prognosis, reporting on this type of tumor is important to guide therapeutic planning, and to identify and track possible complications of its underdiagnosis.

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Leiomiossarcoma de Mama: Relato de caso

Cited by 2 publications

References 9 publications

Retromammary fat, axillary and arm metastases from a retroperitoneal leiomyosarcoma: report of a case with an indolent behaviour

Retromammary fat, axillary and arm metastases from a retroperitoneal leiomyosarcoma: report of a case with an indolent behaviour

Primary Leiomyosarcoma of the Breast Papilla: A Case Report

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