Tratamento de hemorragia intestinal grave decorrente de hipertensão porta, por meio de esplenectomia subtotal e anastomose esplenorrenal proximal

Petroianu, Andy; Neto, J. B.

doi:10.1590/s0100-69912008000400010

Cited by 3 publications

(3 citation statements)

References 37 publications

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“…In a line of research [8][9][10][11][12][13] , the purpose of this study was to verify a possible relationship between the size of the spleen and values of circulating blood elements in patients with schistosomatic splenomegaly.…”

Section: IImentioning

confidence: 99%

Correlation between the values of circulating blood elements with the size of spleen in the presence of schistosomal splenomegaly

et al. 2018

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Purpose: To evaluate a possible relationship between the size of the spleen and values of circulating blood elements in patients with schistosomatic splenomegaly. Methods: Sixty one patients with hepatosplenic schistosomiasis mansoni underwent a clinical exam and peripheral venous blood was collected for a hemogram. The erythrocyte, hemoglobin, hematocrit, leukocyte, and platelet values were determined. All patients underwent abdominal ultrasound to measure the spleen. The hematological test results were compared to the size of the spleen. Results: The size of the spleen varied from 14.0 to 28.4 (19.9 ± 3.7) cm according to the ultrasound image. Thrombocytopenia was observed 58 (95%) patients, leukopenia in 55 (90%) patients, and anemia in 32 (52.4%) patients. Leukopenia was proportional to splenomegaly. Conclusion: Schistosomal splenomegaly leads to leukopenia in direct proportion to the size of the spleen.

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Section: IImentioning

confidence: 99%

Correlation between the values of circulating blood elements with the size of spleen in the presence of schistosomal splenomegaly

et al. 2018

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“…Further studies in this area revealed the possibility of performing this surgical procedure laparoscopically 2 . In his studies, the researcher Petroianu 2 shows this procedure as a new way of treating severe pain caused by spleen ischemia, splenic trauma, myelofibrosis and myeloid metaplasia, cystadenoma in the pancreatic tail, Gaucher disease, and, at last, for the treatment of hemorrhage from intestinal varices, due to portal hypertension 20 .…”

Section: Introductionmentioning

confidence: 99%

Study of the upper pole after subtotal splenectomy in rats

et al. 2022

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Purpose: To evaluate macro/microscopic viability of the upper pole (UP) in rats after 80 days of subtotal splenectomy preserving the upper pole (SSPUP). Methods: Twenty-five male Wistar rats were submitted to SSPUP. After 80 days, the rats were euthanized, and the remaining UP was evaluated macroscopically regarding appearance, color, consistency, length, width, thickness, and presence of fibrosis/necrosis; and microscopically regarding presence of red and white pulp, fibrosis/necrosis. Results: Two rats died during surgery and were removed from the statistical analysis. There was statistically significant increase in length and width between the pre and postoperative in the experimental group, with no significant difference in thickness. In the manipulation group, the macroscopic appearance of the spleen was normal in pre and postoperative, with viability preserved. In the experimental group, two UP of the spleen were not found during the second surgery. Macroscopically, it was observed absence of fibrosis and necrosis in all cases. Microscopically, the white and red pulp were intact in both groups. Two spleens of rats in the manipulation group presented areas with fibrosis and necrosis focus, which were not enough to be considered inviable. Conclusions: The UP of the spleen remained viable in 91.3% of the cases.

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“…Considering the risks inherent to total splenectomy, the spleen's partial preservation is recommended 7,10,11,[17][18][19][20] .…”

Section: Introductionmentioning

confidence: 99%

Effects of inferior splenic lobe pole fixation and gastrosplenic peritoneal membrane section on the vitality of the remanent of subtotal splenectomy in rats

et al. 2015

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PURPOSE:To investigate the vitality of the spleen lower pole after subtotal splenectomy with suture to the stomach and after posterior peritoneal gastro-splenic membrane section, using macro and microscopic evaluations. METHODS:Sixty Wistar rats were used in this study and were randomly distributed in the three groups: Group 1: (n=20), subtotal splenectomy with lower pole preservation, Group 2: (n=20) subtotal splenectomy with lower pole preservation and suture to the stomach, Group 3: subtotal splenectomy with lower pole preservation and posterior peritoneal gastrosplenic ligament section. The animals were sacrificed 45 days after the surgery and the spleen lower poles were removed for macroscopic and microscopic examination. RESULTS:All animals in this series survived. No macroscopic differences were encountered between the groups. Microscopic evaluation observed statistic difference concerning fibrosis between group 1 and 3 (p≤0.05), but the analysis for necrosis and inflammation presented no differences. CONCLUSION:Vitality of the spleen lower pole after subtotal splenectomy is minimally modified when it is fixed to the stomach or when the posterior peritoneal gastrosplenic ligament is resected.

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Tratamento de hemorragia intestinal grave decorrente de hipertensão porta, por meio de esplenectomia subtotal e anastomose esplenorrenal proximal

Cited by 3 publications

References 37 publications

Correlation between the values of circulating blood elements with the size of spleen in the presence of schistosomal splenomegaly

Correlation between the values of circulating blood elements with the size of spleen in the presence of schistosomal splenomegaly

Study of the upper pole after subtotal splenectomy in rats

Effects of inferior splenic lobe pole fixation and gastrosplenic peritoneal membrane section on the vitality of the remanent of subtotal splenectomy in rats

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