Salicilatos isolados de folhas e talos de Salix martiana Leyb. (Salicaceae)

Fernandes, Carromberth Carioca; Cursino, Lorena Mayara de Carvalho; Novaes, Jussival de Abreu Pinheiro; Demetrio, Camilla Avelino; Júnior, Orlando Libório Pereira; Núñez, Cecília Veronica; Amaral, Iêda Leão do

doi:10.1590/s0100-40422009000400029

Cited by 14 publications

(5 citation statements)

References 3 publications

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“…Glycosides are major secondary metabolites in Salicaceae (Binns et al, 1968;Kompantsev and Shinkarenko, 1973;Kompantsev et al, 1974;Nichols-Orians et al, 1992;Fernandes et al, 2009). Phenolic glycosides represent up to 30% of dry plant mass.…”

Section: Phenolic Glycosidesmentioning

confidence: 99%

Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review

et al. 2021

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The Willows (genus Salix), with more than 330–500 species and 200 hybrids, are trees, shrubs or prostrate plants that are widely distributed in Africa, North America, Europe, and Asia. The genus is traditionally used in folk medicine and represents a valuable source of biologically active compounds among them salicin, a prodrug for salicylic acid. Altogether, 322 secondary metabolites were characterized in the genus including flavonoids 94) (flavonols, flavones, flavanones, isoflavones, flavan-3-ols (catechins and procyanidins), chalcones, dihydrochalcone, anthocyanins, dihydroflavonols), phenolic glycosides (76), organic acids (28), and non-phenolic glycosides (17), sterols and terpenes (17), simple phenolics 13) and lignans 7) in addition to volatiles and fatty acids (69). Furthermore, willows exert analgesic, anti-inflammatory, antioxidant, anticancer, cytotoxic, antidiabetic, antimicrobial, antiobesity, neuroprotective and hepatoprotective activities. The current review provides an updated summary of the importance of willows, their chemical composition and pharmacological activities.

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Section: Phenolic Glycosidesmentioning

confidence: 99%

Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review

et al. 2021

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“…1 Some of its relevant compounds are lignins, terpenoids, coumarins, alkaloids, saponins and flavonoids. 2,3 Anti-inflammatory and antibacterial activities are reported for Salicaceae species. 4,5 The Casearia genus belongs to the family Salicaceae and the secondary metabolites of this genus include terpenoids, flavonoids, glycosides and phenylpropanoids.…”

Section: Introductionmentioning

confidence: 99%

Phytochemistry investigation of Casearia arborea (Rich.) Urb. (Salicaceae) and antimicrobial analysis of its diterpene

et al. 2018

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A phytochemical investigation from aerial parts of Casearia arborea (Rich.) Urb. (Salicaceae) led to isolation and identification of: sitosterol, 4-en-stigmast-3-one, 13-hydroxy-trans-ent-cleroda-3,14-diene,3-hydroxy-2-oxo-trans-ent-cleroda-3,14-diene (kolavelone), a mixture of 13-hydroxy-trans-ent-cleroda-3,14-diene and an ester ethyl hexadecanoate, kaempferol-3-O-α-L-arabinofuranoside and 4',5,7-trihydroxy-3',5'-dimethoxyflavone (tricin). The compounds have been described for the first time in this species. Five trihydroxy-flavone-hexoside derivatives have been identified by LC-ESI-HR-MS. The antimicrobial activity of kolavelone was evaluated against strains of Staphylococcus, Bacillus, Pseudomonas, Shigella and Candida spores, and its minimum inhibitory concentration (MIC) was determined. The results showed the antimicrobial activity of kolavelone against several bacteria and Candida tropicalis indicating its potential use as antimicrobial agent.

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“…An aromatic coumaric acid derivative named trichocarposide (m/z 415.15), was observed. Trichocarposide has been found to be one of the active ingredients in the methanolic extract of Salix martiana Leyb that exhibits strong DPPH antioxidant activity [32]. A diterpene-based alkaloid, icaceine (m/z 358.24), known to exhibit anticonvulsant properties, was detected.…”

Section: Metabolite Profilingmentioning

confidence: 99%

Non-Targeted Secondary Metabolite Profile Study for Deciphering the Cosmeceutical Potential of Red Marine Macro Alga Jania rubens—An LCMS-Based Approach

Dixit

Reddy

2017

Cosmetics

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This study aims to unveil the cosmeceutical traits of Jania rubens by highlighting its mineral composition, antioxidant potential, and presence of bioactive molecules using non-targeted metabolite profiling. This study showed that among minerals, (macro), Ca (14790.33 + 1.46 mg/100 g dry weight (DW)) and in (micro) Fe (84.93 + 0.89 mg/100 g DW) was the highest. A total of 23 putative metabolites in the +ESI (Electrospray Ionization) mode of LCMS-TOF (Liquid Chromatography Mass Spectrometry-Time of Flight) were detected. Two anthocyanins-malonylshisonin and 4-demalonylsalvianin (m/z 825.19; anti-aging, antioxidant, anticancer properties) were detected. Two flavonoids, viz, medicocarpin and agecorynin C, 4-O-methylglucoliquiritigenin-a flavonoid-7-O-glycoside, and 5,6,7,8,3 ,4 ,5-heptamethoxyflavone, a polymethoxygenated flavone (m/z 415.15), were detected. Maclurin 3-C-(2 ,3 ,6-trigalloylglucoside) (m/z 863.15) (antioxidant, antimicrobial and anticancer traits) and theaflavonin (m/z 919.18), belonging to the class of theaflavins (whitening and anti-wrinkle agent), were obtained. Pharmacologically active metabolites like berberrubin (m/z 305.1; antitumor activity), icaceine (m/z 358.24; anticonvulsant properties), agnuside (m/z 449.15; constituent for treatment of premenstrual syndrome), γ-coniceine (m/z 108.12; formulations to treat breast cancer), eremopetasitenin B2, and eremosulphoxinolide A (m/z 447.18; therapeutic effect of allergy and asthma) were observed. 6-O-Methylarmillaridin (m/z 445.18) (antimicrobial and antifungal) and simmondsin 2-ferulate, (m/z 534.21) (insecticidal, antifungal and antifeedant) were detected. Aromatic lignans, viz, 8-Acetoxy-4-methoxypinoresinol, sesartemin, and cubebinone (m/z 413.16), in addition to an aromatic terpene glycoside, tsangane L3 glucoside (m/z 357.23), were detected. Zizybeoside I, benzyl gentiobioside, and trichocarposide were also detected. The determination of antioxidant potential was performed through assays such as like DPPH (2,2-diphenyl-1-picrylhydrazyl), FRAP (Ferric Ion Reducing Antioxidant Power), ABTS (2,2-azino-bis(3-ethylbenz-thiazoline-6-sulfonic acid)), and total antioxidants. Therefore, this study progresses the probability for the inclusion of J. rubens as an ingredient in modern day cosmetic formulations.

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Salicilatos isolados de folhas e talos de Salix martiana Leyb. (Salicaceae)

Cited by 14 publications

References 3 publications

Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review

Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review

Phytochemistry investigation of Casearia arborea (Rich.) Urb. (Salicaceae) and antimicrobial analysis of its diterpene

Non-Targeted Secondary Metabolite Profile Study for Deciphering the Cosmeceutical Potential of Red Marine Macro Alga Jania rubens—An LCMS-Based Approach

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