Estudio analitico de especies oxigenadas en el aceite de teobroma ozonizado

Gómez, Maritza F. Díaz; Téllez, Goitybell Martínez; Hernández, Rosa Ibis Meneau; Alaiz, Manuel; Garcés, Rafael

doi:10.1590/s0100-40422008000300028

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…In addition, IFN-g knockout mice show accelerated tumor growth and M2-type TAMs during urethane-induced lung cancer. However, lung tumor growth is inhibited in IL-4R knockout mice and TAMs phenotype presents M1-type (40). These results also indicate that IFN-g and IL-4 play an antagonistic role in the differentiation of TAMs and that targeting IL-4 in the TME may contribute to lung cancer treatment.…”

Section: Interleukins and Chemokinesmentioning

confidence: 68%

The Crosstalk Between Tumor-Associated Macrophages (TAMs) and Tumor Cells and the Corresponding Targeted Therapy

Ding

2020

Front. Oncol.

122

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Tumor microenvironment (TME) is composed of tumor cells and surrounding non-tumor stromal cells, mainly including tumor associated macrophages (TAMs), endothelial cells, and carcinoma-associated fibroblasts (CAFs). The TAMs are the major components of non-tumor stromal cells, and play an important role in promoting the occurrence and development of tumors. Macrophages originate from bone marrow hematopoietic stem cells and embryonic yolk sacs. There is close crosstalk between TAMs and tumor cells. With the occurrence of tumors, tumor cells secrete various chemokines to recruit monocytes to infiltrate tumor tissues and further promote their M2-type polarization. Importantly, M2-like TAMs can in turn accelerate tumor growth, promote tumor cell invasion and metastasis, and inhibit immune killing to promote tumor progression. Therefore, targeting TAMs in tumor tissues has become one of the principal strategies in current tumor immunotherapy. Current treatment strategies focus on reducing macrophage infiltration in tumor tissues and reprogramming TAMs to M1like to kill tumors. Although these treatments have had some success, their effects are still limited. This paper mainly summarized the recruitment and polarization of macrophages by tumors, the support of TAMs for the growth of tumors, and the research progress of TAMs targeting tumors, to provide new treatment strategies for tumor immunotherapy.

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Section: Interleukins and Chemokinesmentioning

confidence: 68%

The Crosstalk Between Tumor-Associated Macrophages (TAMs) and Tumor Cells and the Corresponding Targeted Therapy

Ding

2020

Front. Oncol.

122

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Effect of the ozonization process on the quality of peanuts and crude oil

Alencar

Faroni²,

Soares³

et al. 2011

Rev. bras. eng. agríc. ambient.

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The purpose of this study was to evaluate the effect of ozone on the quality of peanut grains and crude oil extracted from these grains. Peanut samples of 1 kg were used, with a moisture content of 8.0% w.b. and stored in 3 L glass recipients. The ozonization process utilized ozone gas concentrations of 13 and 21 mg L . Evaluation of peanut quality consisted of analysis for moisture content, electrical conductivity, lipid concentration and peanut color. The qualitative parameters of the crude oil evaluated were free fatty acids, peroxide index and iodine index. In general there was no alteration in peanut quality due to ozone, except for the coloration of the peanuts. With regard to parameters related to the crude oil extracted from the peanut, there were no qualitative alterations due to ozone exposure. It was concluded that, despite depigmentation of the skin surrounding the peanuts, the quality of the peanuts and the extracted crude oil is not affected by exposure to ozone gas at concentrations up to 21 mg L . Para avaliação da qualidade dos grãos foram analisados os parâmetros teor de água, condutividade elétrica, teor de lipídios e coloração dos grãos. Quantificaram-se, para a avaliação da qualidade do óleo bruto, o teor de ácidos graxos livres, o índice de peróxido e o índice de iodo. Em geral, não ocorreu alteração da qualidade do amendoim em virtude a exposição ao ozônio, exceto para a variável coloração dos grãos. Com relação aos parâmetros relacionados ao óleo bruto, não ocorreram alterações qualitativas devido a exposição ao ozônio. Concluiu-se que, apesar de ocorrer despigmentação da película que envolve os grãos de amendoim, a qualidade dos grãos e do óleo bruto extraído não é afetada pela exposição ao gás ozônio em concentrações de até 21 mg L -1

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Estudio analitico de especies oxigenadas en el aceite de teobroma ozonizado

Cited by 2 publications

References 6 publications

The Crosstalk Between Tumor-Associated Macrophages (TAMs) and Tumor Cells and the Corresponding Targeted Therapy

The Crosstalk Between Tumor-Associated Macrophages (TAMs) and Tumor Cells and the Corresponding Targeted Therapy

Effect of the ozonization process on the quality of peanuts and crude oil

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