Volatile constituents of the oils from Povedadaphne Quadriporata (lauraceae) from "Alberto M. Brenes" biological preserve, Costa Rica

Cicció, José F.; Chaverri, Carlos

doi:10.1590/s0100-40422008000300027

Cited by 11 publications

(6 citation statements)

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“… a: the identified constituents are listed in their order of elution from a non-polar column (Varian FactorFour VF-5ms); b: from curzerene and furanodiene. Quantitative data are affected by thermal rearrangement; c: Cicció and Chaverri (2008) ; RI: retention indices; UI: undetermined isomer. …”

Section: Resultsmentioning

confidence: 99%

Therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products

Houël

González

Bessière

et al. 2015

Mem. Inst. Oswaldo Cruz

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This study examined whether the antidermatophytic activity of essential oils (EOs) can be used as an indicator for the discovery of active natural products against Leishmania amazonensis. The aerial parts of seven plants were hydrodistilled. Using broth microdilution techniques, the obtained EOs were tested against three strains of dermatophytes (Trichophyton mentagrophytes, Microsporum gypseum and Microsporum canis). To compare the EOs antifungal and antiparasitic effects, the EOs activities against axenic amastigotes of L. amazonensis were concurrently evaluated. For the most promising EOs, their antileishmanial activities against parasites infecting peritoneal macrophages of BALB/c mice were measured. The most interesting antifungal candidates were the EOs from Cymbopogon citratus, Otacanthus azureus and Protium heptaphyllum, whereas O. azureus, Piper hispidum and P. heptaphyllum EOs exhibited the lowest 50% inhibitory concentration (IC50) values against axenic amastigotes, thus revealing a certain correspondence between both activities. The P. hispidum EO was identified as the most promising product in the results from the infected macrophages model (IC50: 4.7 µg/mL, safety index: 8). The most abundant compounds found in this EO were sesquiterpenes, notably curzerene and furanodiene. Eventually, the evaluation of the antidermatophytic activity of EOs appears to be an efficient method for identifying new potential drugs for the treatment of L. amazonensis.

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Section: Resultsmentioning

confidence: 99%

Therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products

Houël

González

Bessière

et al. 2015

Mem. Inst. Oswaldo Cruz

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“…Linalool was one of the constituents found in all species, however its presence was only unanimous in stems, which was not the case in leaves. This particularity can also be found in other species of Lauraceae, where the compound was found solely or mostly in stems (Chaverri & Cicció, 2008;Alcântara et al, 2010). This monoterpene is of particular importance to the cosmetics industry, as it is commonly used as a perfume fixative.…”

Section: Resultsmentioning

confidence: 62%

Ocotea(Lauraceae) Amazonian essential oils chemical composition and their tyrosinase inhibition to use in cosmetics

Yamaguchi¹,

Pedrosa²,

Vasconcellos³

et al. 2020

BLACPMA

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“…Na maioria dos óleos essenciais de Lauraceae reportados na literatura observa-se a predominância de sesquiterpenos, principalmente de hidrocarbonetos sesquiterpênicos (Gottlieb et al, 1981;Cicció & Chaverri, 2008;Telascrea et al, 2008).…”

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Composição química e atividade biológica dos óleos essenciais das folhas e caules de Rhodostemonodaphne parvifolia Madriñán (Lauraceae)

et al. 2010

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RESUMOOs óleos essenciais das folhas e caules de Rhodostemonodaphne parvifolia coletada na Reserva Florestal Adolpho Ducke foram obtidos por hidrodestilação e analisados por cromatografia em fase gasosa com detector de ionização de chama e espectrometria de massas. Treze constituintes foram identificados nas folhas, dos quais o b-cariofileno foi o que apresentou maior percentual (41,30%). Nos caules foram identificados quinze compostos, com predominância dos sesquiterpenos b-cariofileno (16,20%) e epi-cedrol (13,30%) e do monoterpeno linalol (15,40%). Os óleos foram analisados em ensaios químicos, de sequestro do radical livre DPPH, e enzimáticos, de inibição da enzima acetilcolinesterase. Nos ensaios de sequestro de radicais livres, apesar de terem se mostrado ativos em ensaios qualitativos, os óleos essenciais apresentaram fraca atividade antioxidante no ensaio quantitativo (inativos em concentração inferior a 1.000 mg/mL). A inibição da acetilcolinesterase só foi observada nos óleos essenciais das folhas. A composição química e a atividade biológica destes óleos estão sendo relatadas pela primeira vez neste trabalho. PALAVRAS-CHAVE:Rhodostemonodaphne parvifolia, óleo essencial, antioxidante, anticolinesterase. Composition and biology activity of essential oils from leaves and stems of Rhodostemonodaphne parvifolia Madriñán (Lauraceae) ABSTRACTThe essential oils of leaves and stems of Rhodostemonodaphne parvifolia collected in the Adolpho Ducke Forest Reserve were obtained by hydrodistillation and analyzed by GC-FID and GC-MS. Thirteen components were identified in the leaf oil, of which b-caryophyllene was the major (41.30%). Fifty components were identified in the stem oil, among them the sesquiterpenes b-caryophyllene (16.20%) and epi-cedrol (13.30%), together with the monoterpene linalool (15.40%). The essential oils were analyzed at chemical, DPPH free radical scavenging; and enzymatic bioassays, acetylcholinesterase inhibition. At antioxidant DPPH assays, the oils showed to be active at the qualitative assay but only weakly active at quantitative test (inactive at concentration lower than 1,000 mg/mL). The inhibition of acetylcholinesterase was detected only in leaves essential oils. This paper describes for the first time the composition of these essential oils and their biological activities.

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Volatile constituents of the oils from Povedadaphne Quadriporata (lauraceae) from "Alberto M. Brenes" biological preserve, Costa Rica

Cited by 11 publications

References 4 publications

Therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products

Therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products

Ocotea(Lauraceae) Amazonian essential oils chemical composition and their tyrosinase inhibition to use in cosmetics

Composição química e atividade biológica dos óleos essenciais das folhas e caules de Rhodostemonodaphne parvifolia Madriñán (Lauraceae)

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