2012
DOI: 10.1590/s0074-02762012000800006
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Abstract: To cope with oxidative stress, Candida albicans possesses several enzymes involved in a number of biological processes, including superoxide dismutases (Sods) and glutaredoxins (Grxs)

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Cited by 24 publications
(11 citation statements)
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“…albicans virulence although they are induced under different growth conditions, consistent with the low expression levels we observed in exponentially grown wild-type cells. Sod1 is known to be induced under hyphal-promoting conditions and it has been implicated in protection against ROS generated by menadione and macrophages [ 21 , 56 ]. Sod1 expression is repressed during stationary phase as a defense mechanism to evade copper toxicity [ 21 , 22 ].…”
Section: Discussionmentioning
confidence: 99%
“…albicans virulence although they are induced under different growth conditions, consistent with the low expression levels we observed in exponentially grown wild-type cells. Sod1 is known to be induced under hyphal-promoting conditions and it has been implicated in protection against ROS generated by menadione and macrophages [ 21 , 56 ]. Sod1 expression is repressed during stationary phase as a defense mechanism to evade copper toxicity [ 21 , 22 ].…”
Section: Discussionmentioning
confidence: 99%
“…This technique has not been widely used for this species [21], but has been largely used to type Cryptococcus neoformans [16,31]. …”
Section: Discussionmentioning
confidence: 99%
“…The method of Chaves and da Silva (2012) was used with some modifications to determine the sensitivity of C. tropicalis to NaCl. Ten microliters volumes of NGY-grown yeast cells was transferred to 100 μL of Sabouraud Dextrose broth, with addition of NaCl (0.03–30%) in 96 wells microtiter plates [TPP, 92096], incubated at 35°C for 48 h. Growth determination was visually observed trough the turbidity perceptible within each well.…”
Section: Methodsmentioning
confidence: 99%