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citations
Cited by 19 publications
(22 citation statements)
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References 29 publications
(28 reference statements)
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“…However, due to the moderate estimates for NPV, our fi ndings suggest that patients with negative RDT results should undergo further investigation with additional serological tests and examination of bone marrow aspirates. Polymerase chain reaction for the detection of Leishmania deoxyribonucleic acid (DNA) in bone marrow or peripheral blood specimens might also be useful to confi rm or rule out VL diagnosis in challenging situations [23][24][25][26] .…”
Section: Ethical Considerationsmentioning
confidence: 99%
“…However, due to the moderate estimates for NPV, our fi ndings suggest that patients with negative RDT results should undergo further investigation with additional serological tests and examination of bone marrow aspirates. Polymerase chain reaction for the detection of Leishmania deoxyribonucleic acid (DNA) in bone marrow or peripheral blood specimens might also be useful to confi rm or rule out VL diagnosis in challenging situations [23][24][25][26] .…”
Section: Ethical Considerationsmentioning
confidence: 99%
“…Visceral leishmaniasis detection using traditional methods is hampered by necessity for invasive procedures, low sensitivity, and the extended time to obtain results. PCR for the detection of L. infantum DNA in peripheral blood is a non-invasive alternative for diagnosis offering enhanced sensitivity, and is particularly useful when disease is suspected in patients with negative parasitological results (Reithinger et al 2007;Fraga et al 2010).…”
Section: Discussionmentioning
confidence: 99%
“…• Chagas disease 35 • Quilty effect, rejection, C myocarditis reactivation, fi brosis, hypertrophy, and ischemia; as well as lymphocytic cellular infi ltration of myocarditis 35 • Cardiovascular development 167,168 • Morphology and mechanical properties of the atrial intima 167 • Acquired immune defi ciency syndrome 204 • CD4+ T-cell 2 count and HIV viral load, fecal calprotectin, and bowel ultrasound, with the latter evaluating bowel wall thickness and mesenteric lymph nodes 204 Bone marrow PCR, PCR-RFLP, histologic evaluation (Giemsa staining), bone marrow culture 205 • Visceral leishmaniasis 205 • Leishmania DNA 205 Skin Histologic evaluation (H&E), immunoperoxidase 206 • Primary cutaneous plasmacytosis 206 • Search for cell infi ltration of dermis, clusters of B-lymphocytes CD20 reactive, and expression of κ light chains and λ light chains to diagnosis rare disease 206 • Exposure to endocrine disruptors during pregnancy and infancy 189 • Levels of non-POPs (including MEHP, OP, and 4-NP), and PBDEs 189 …”
Section: Agonal Factorsmentioning
confidence: 99%