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citations
Cited by 152 publications
(111 citation statements)
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References 19 publications
(17 reference statements)
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“…The promising trypanocidal activity exhibited by the essential oil from P. ovatum leaves can be justified by the following terpenes: β-caryophyllene (14.0 %), p-cymene (0.3 %), limonene (1.8 %), spathulenol (17.6 %) and caryophyllene oxide (16.4 %), as previously identified in the essential oil from different species of Lippia spp, with recognised antiparasitic activity (Escobar et al 2010). The compound α-pinene (1.2 %), which is also found in the essential oil from Schinus terebinthifolius, has recognised trypanocidal activity (Sartorelli et al 2012).…”
Section: Resultsmentioning
confidence: 56%
“…The promising trypanocidal activity exhibited by the essential oil from P. ovatum leaves can be justified by the following terpenes: β-caryophyllene (14.0 %), p-cymene (0.3 %), limonene (1.8 %), spathulenol (17.6 %) and caryophyllene oxide (16.4 %), as previously identified in the essential oil from different species of Lippia spp, with recognised antiparasitic activity (Escobar et al 2010). The compound α-pinene (1.2 %), which is also found in the essential oil from Schinus terebinthifolius, has recognised trypanocidal activity (Sartorelli et al 2012).…”
Section: Resultsmentioning
confidence: 56%
“…Although a previous study has demonstrated the leishmanicidal activity of Lippia origanoides essential oil, with a relative amount of carvacrol greater than 35% (Escobar et al, 2010), this is the fi rst report on the leishmanicidal properties of essential oil from a new L. sidoides accession in which carvacrol, rather than thymol, is the main constituent. The composition of the carvacrol-rich essential oil herein evaluated (LSEO104) was similar to the one characterized by Cavalcanti et al (2010).…”
Section: Resultsmentioning
confidence: 65%
“…The leishmanicidal and trypanocidal activity of essential oils from Lippia spp have been already demonstrated in some studies (Sulsen et al, 2006;Escobar et al, 2010 …”
Section: Discussionmentioning
confidence: 93%
“…Thymol is a monoterpene phenol with many pharmaceutical properties including the following: anthelmintic (CAMURÇA-VASCONCELOS et al, 2007), acaricide , anti-Leishmania infantum (MORAIS et al 2014), anti-Trypanosoma cruzi (ESCOBAR et al, 2010) and anti-Echinococcus multilocularis (MARÍA & CELINA, 2014). However, thymol is more toxic than many esters, therefore, the synthesis of TA was performed to obtain a derivative of thymol with improved biological activity and less toxicity (MORAIS et al, 2014).…”
Section: Discussionmentioning
confidence: 99%