2010
DOI: 10.1590/s0074-02762010000200006
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Abstract: Infection with some genotypes of human papillomavirus (HPV) is the most important risk factor associated with cervical cancer (CC

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Cited by 15 publications
(11 citation statements)
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“…However, the cervix is histologically different from lymphoid tissues which are localized very far from the cervical epithelium by thick myometrial tissue of the cervix. The same situation has been observed in HPV infection where E6-E7 oncogenes are frequently expressed in cervical neoplastic lesions and which are equally targets for cytotoxic T lymphocyte response in patients with cervical neoplasia [34]. …”
Section: Discussionmentioning
confidence: 54%
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“…However, the cervix is histologically different from lymphoid tissues which are localized very far from the cervical epithelium by thick myometrial tissue of the cervix. The same situation has been observed in HPV infection where E6-E7 oncogenes are frequently expressed in cervical neoplastic lesions and which are equally targets for cytotoxic T lymphocyte response in patients with cervical neoplasia [34]. …”
Section: Discussionmentioning
confidence: 54%
“…Amplified fragment was detected by hybridization using 32 P-labeled-BamH1-A probe prepared with a random primer DNA-labeling kit (Stratagene) [33]. The hybridization was carried out in a modified solution described by Ausubel et al [34] with 10 6  cpm/ml of the labeled BALF1 probe.…”
Section: Methodsmentioning
confidence: 99%
“…In southeastern Mexico, the low-risk genotypes (HPV 6 and 11) had a higher prevalence, [29] but in patients with cervical intraepithelial neoplasia, the HPV 16 and 58 were prevalent (30.6 and 24%, respectively); HPV 18 was not identified [30]. Meanwhile, in African countries, the prevalence of HPV 16, 33, and 58 was greater than that of other types [31].…”
Section: Discussionmentioning
confidence: 99%
“…The highest prevalence of HPV 58 is in Latin America and Asia. Studies have found high prevalence of this type in China, Japan, Mexico, Costa Rica, Colombia, and Brazil [46, 19, 20]. …”
Section: Discussionmentioning
confidence: 99%