Epidemiology of leishmaniasis in Ecuador: current status of knowledge - A review

Calvopiña, Manuel; Armijos, Rodrigo X.; Hashiguchi, Yoshihisa

doi:10.1590/s0074-02762004000700001

Cited by 65 publications

(83 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…as causative agents for human cutaneous (CL) and mucocutaneous leishmaniases (MCL) (Calvopiña et al, 2004 (Calvopiña et al, 2001(Calvopiña et al, , 2004Kato et al, 2008). Although infection with L. (V.) naiffi was detected in Lu.…”

Section: Leishmania (Leishmania) Major-like L (L) Mexicana L (Lmentioning

confidence: 99%

First human cases of Leishmania (Viannia) naiffi infection in Ecuador and identification of its suspected vector species

et al. 2013

Self Cite

View full text Add to dashboard Cite

Section: Leishmania (Leishmania) Major-like L (L) Mexicana L (Lmentioning

confidence: 99%

First human cases of Leishmania (Viannia) naiffi infection in Ecuador and identification of its suspected vector species

et al. 2013

Self Cite

View full text Add to dashboard Cite

“…According to the information reviewed, Le. (V.) panamensis is the only parasite species found in the Northern part of Bolívar province [7]. More studies are needed to further identify the parasite species circulating in Echeandía and to further evaluate the PCR assays used in this study.…”

Section: Resultsmentioning

confidence: 99%

“…Various other studies were published in local medical journals in the 1950's [3,4] and the first and only unconfirmed report of VL was reported in 1949 [5]. This information has been listed chronologically in other publications [6] and has been reviewed elsewhere [7]. More recently, since the 1990s, several scientist have contributed to the knowledge of the parasites [8][9][10][11], the vectors [12][13][14][15][16], the clinical forms [17][18][19][20], prevention and treatment strategies [21][22][23] and other aspects of the disease in Ecuador, many studies compiled in a series of book publications [24][25][26][27][28][29][30][31].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Breve reseña y detección de parásitos <em>Leishmania</em> en biopsias de piel de pacientes procedentes de Echeandía, provincia de Bolívar, Ecuador

León

Erkelenz

Reck

et al. 2014

Av. Cienc. Ing. (Quito)

View full text Add to dashboard Cite

Leishmaniasis is an important neglected tropical disease and the cause of significant morbidity in endemic countries such as Ecuador. It is transmitted by the bite of infected sand flies (Diptera Psychodidae) and has been reported from at least 22/24 provinces in the country including the foothills of the Andean mountains. Herein, we report the detection of Leishmania parasites, using PCR assays, in skin biopsies taken from ulcers of leishmaniasis patients from Echeandía in the province of Bolívar, Ecuador. These results suggest that most of the patients were infected with parasites from the braziliensis complex that among other species, includes Leishmania (Viannia) panamensis which is the most common species that causes cutaneous leishmaniasis in the Pacific coast, and Leishmania (V.) braziliensis, the cause of mucocutaneous lesions and significant patient disfiguration. More studies are needed to further identify the parasite species present in this area and address aspects of the parasite's life cycle and transmission dynamics. Our preliminary results showed that the R174 and R798 18 S ribosomal DNA primers used in this study are effective to amplify Leishmania DNA and would be a useful tool to molecularly detect New World parasites causing tegumentary leishmaniasis.Keywords. PCR, Echeandia, leishmaniasis, skin biopsies. ResumenLa leishmaniasis es una importante enfermedad tropical desatendida y es la causa de significativa morbilidad en países endémicos como el Ecuador. La enfermedad es transmitida por la picadura de flebótomos (Diptera:Psychodidae) infectados y ha sido reportada en al menos 22/24 provincias del Ecuador incluyendo las estribaciones de la cordillera de los Andes. En esta publicación reportamos la detección de parásitos de Leishmania mediante ensayos de PCR en biopsias de piel de pacientes con diagnóstico de leishmaniasis provenientes de la zona de Echeandía en la Provincia de Bolívar, Ecuador. Los resultados sugieren que la mayoría de los pacientes fueron infectados por parásitos pertenecientes al complejo braziliensis que incluye entre otras especies a Leishmania (Viannia) panamensis, el parásito más abundante en la costa Pacífica y causa de leishmaniasis cutánea y Leishmania (V.) braziliensis, la causa de lesiones mucocutáneas y significativa desfiguración del paciente. Más estudios son necesarios para identificar las especies del parásito que circulan en esta zona y abordar otros aspectos de los ciclos naturales de cada especie del parásito y la dinámica de transmisión. Los resultados preliminares muestran que los cebadores R174 and R798 del ADN 18 S ribosomal usados en este estudio son efectivos para amplificar ADN de Leishmania y pueden ser una herramienta útil en la detección de parásitos del Nuevo Mundo que causan leishmaniasis tegumentaria.Palabras Clave. PCR, Echeandia, Leishaniasis, biopsias de piel.

show abstract

“…2 In Ecuador, ATL is endemic in 21 of the 24 provinces; CL is a public health problem because of its wide distribution, mainly in rural subtropical and tropical areas of the Pacific and Amazon regions, as well as in some inter-Andean valleys. 6,7 Ecuador has one of the highest incidences of ATL in the Americas, with 11,983 cases documented from the years 2004-2010. The disease occurs in all of the recognized ATL forms: CL, MCL, and DCL, with CL the most widely distributed form in the country.…”

Section: Introductionmentioning

confidence: 99%

Coinfection of Leishmania guyanensis and Human Immunodeficiency Virus–Acquired Immune Deficiency Syndrome: Report of a Case of Disseminated Cutaneous Leishmaniasis in Ecuador

Calvopiña

Aguirre²,

Cevallos

et al. 2017

Am J Trop Med Hyg

Self Cite

View full text Add to dashboard Cite

Abstract. Reported herein is the first case of Leishmania-human immunodeficiency virus (HIV) coinfection in Ecuador. In Ecuador, HIV infections overlap endemic areas of leishmaniasis. Immunosuppression is a wellestablished risk factor for developing severe disease. This is a severe case of a 32-year-old man presenting with disseminated pleomorphic ulcers, papules, and cutaneous plaque-like lesions over his whole body. Numerous amastigotes were observed in both skin scrapings and biopsies. The sequence of the cytochrome b gene confirmed the presence of Leishmania guyanensis. The patient was treated but failed to respond to meglumine antimoniate and amphotericin B. Six months later, the patient died due to bacterial septic shock.

show abstract

Epidemiology of leishmaniasis in Ecuador: current status of knowledge - A review

Abstract: Although leishmaniasis is regarded as a significant health problem in

Cited by 65 publications

References 48 publications

First human cases of Leishmania (Viannia) naiffi infection in Ecuador and identification of its suspected vector species

First human cases of Leishmania (Viannia) naiffi infection in Ecuador and identification of its suspected vector species

Breve reseña y detección de parásitos <em>Leishmania</em> en biopsias de piel de pacientes procedentes de Echeandía, provincia de Bolívar, Ecuador

Coinfection of Leishmania guyanensis and Human Immunodeficiency Virus–Acquired Immune Deficiency Syndrome: Report of a Case of Disseminated Cutaneous Leishmaniasis in Ecuador

Contact Info

Product

Resources

About