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Cited by 27 publications
(26 citation statements)
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“…This has been previously demonstrated in adult animals (Magalhães et al 1986, Coutinho et al 2003, Coutinho 2004 due to the inflammatory process caused by S. mansoni eggs (Mota & Sleigh 1984, Sleigh et al 1986). Liver pathology around mature eggs depends on, among other factors, the host nutritional status (Coutinho et al 1997, Oliveira et al 2004).…”
Section: Table IVsupporting
confidence: 54%
See 1 more Smart Citation
“…This has been previously demonstrated in adult animals (Magalhães et al 1986, Coutinho et al 2003, Coutinho 2004 due to the inflammatory process caused by S. mansoni eggs (Mota & Sleigh 1984, Sleigh et al 1986). Liver pathology around mature eggs depends on, among other factors, the host nutritional status (Coutinho et al 1997, Oliveira et al 2004).…”
Section: Table IVsupporting
confidence: 54%
“…Liver pathology around mature eggs depends on, among other factors, the host nutritional status (Coutinho et al 1997, Oliveira et al 2004). Liver injury was moderate when compared with wellnourished control mice (Coutinho et al 1997(Coutinho et al , 2003. However, the effects of schistosome parasitism on lactation are unknown.…”
Section: Table IVmentioning
confidence: 99%
“…In this way, nutrition may interfere in all these steps, once protein synthesis occur in all these processes. For this reason, the host nutritional status may be considered as a contributory factor to the remodeling of periovular granulomas of hepatic schistosomiasis and shistosomal granuloma in undernourished mice can be taken as an adequate model for studies on the dynamics of hepatic fibrosis (Coutinho et al 2003).…”
Section: Discussionmentioning
confidence: 99%
“…The following parameters were calculated for granulomas: size, volume density, and numerical density. The sectional area of the fibrous tissue red stained was directly measured and calculated as a percentage of the total area examined, as previously described (Barbosa Jr. 2001, Coutinho et al 2003.…”
Section: Experimental Groupsmentioning
confidence: 99%
“…Various attempts to induce the pipe-stem like liver fibrosis in undernourished mice have been unsuccessful, such as: shifting from a deficient to a balanced diet and vice-versa (Coutinho et al 2003); repeated infections five times at 15-day intervals (Coutinho et al 2007) and assays with BALB/c and C57BL/10 inbred mouse strains (Coutinho 2004).…”
Section: Liver Pathology and Schistosomiasis: The Importance Of The Hmentioning
confidence: 99%