Molluscicidal activity of Physalis angulata L. extracts and fractions on Biomphalaria tenagophila (d'Orbigny, 1835) under laboratory conditions

Antimicrobial activity of the extracts and physalin D fromPhysalis alkekengiand evaluation of antioxidant potential of physalin D

“…12.2 ± 1.5 14.0 ± 0.7 32.4 ± 1.2 -E. faecalis 9.0 ± 1.9 9.8 ± 1.9 21.6 ± 1.1 -B. subtilis 11.2 ± 1.9 13.8 ± 1.3 30.4 ± 1.1 -B. cereus 14.4 ± 0.5 14.8 ± 1.5 27.2 ± 2.4 -Gram(-) bacteria E. coli 6.0 ± 2.4 8.2 ± 1.8 28.4 ± 1.1 -P. aeruginosa 7.6 ± 1.1 10.2 ± 2.6 25.0 ± 1.9 -E. cloacae 9.8 ± 2.7 10.6 ± 0.5 22.8 ± 3.7 -K. pneumoniae 7.8 ± 2.0 7.8 ± 0.4 25.0 ± 2.5 -P. vulgaris 6.0 ± 1.0 7.8 ± 1.3 22.0 ± 1.6 -Fungi C. albicans -6.2 ± 0.8 -23.8 ± 0.8 C. krusei -3.8 ± 0.4 -26.6 ± 1.5 C. glabrata -6.2 ± 0.4 -29.2 ± 1.9 C. tropicalis ---21.2 ± 1.9 C. paraphilosis ---22.6 ± 2.5 a In the literature, there is no report about the antioxidant activity of physalins or the extracts of Physalis species. Our report is the first for physalin D. Previous phytochemical studies on the aerial parts of Physalis plants have led to the identification of physalins, which are believed to be the bioactive compounds of the genus Physalis (Januário et al, 2002;Dos Santos et al, 2003;Wu et al, 2004;Choudhary et al, 2005;Lee & Houghton, 2005;Magalhaes et al, 2006;Damu et al, 2007;Castro et al, 2008). However, there is relatively little information in the literature regarding the steroid content of the calyces of Physalis species (Dinan et al, 1997;Qiu et al, 2008).…”

“…Previous studies have focused on the isolation and characterization of secondary metabolites, whereas it has been demonstrated that some of the extracts or active principles obtained from Physalis species have a broad spectrum of biological activities, including antileukemic, antitumor, immunomodulator, cytotoxic, antimycobacterial, antimicrobial, molluscicidal, antihepatoma, and antinociceptive activities in recent studies (Chiang et al, 1992a(Chiang et al, , 1992bJanuário et al, 2002;Shim et al, 2002;Su et al, 2002;Dos Santos et al, 2003;Soares et al, 2003;Wu et al, 2004;Choudhary et al, 2005;Lee & Houghton, 2005;Silva et al, 2005;Bastos et al, 2006;Magalhaes et al, 2006;Damu et al, 2007;Castro et al, 2008). It has been previously reported that the crude extract (i.e.…”

Antinociceptive effect of the aqueous extract obtained from roots of Physalis angulata L. on mice

“…It is distributed throughout the tropical and subtropical regions of the world (Kissmann and Groth, 1995;Santos et al, 2003). Extracts or infusions from this plant have been used in various countries in popular medicine as a treatment for a variety of illnesses, such as malaria, asthma, hepatitis, dermatitis and rheumatism (Chiang et al, 1992a;Lin et al, 1992;Santos et al, 2003;Soares et al, 2003). In Brazil, Physalis angulata is popularly known as "Camapu", "Bucho de Rã", "Juá de Capote" or "Mata-Fome" (Branch and Silva, 1983), and its juice is considered to be sedative and depurative against rheumatism and earache.…”

“…The whole plant cooked is recommended in baths for inflammatory processes, such as rheumatism (Lorenzi, 1982). It has been demonstrated that some of the extracts or active principles obtained from Physalis angulata have a broad spectrum of biological activities, including antibacterial, molluscicidal, antiprotozoal, anticancer, cytotoxic and immunomodulatory activities (Kastelein and Camargo, 1990;Lee et al, 1991;Chiang et al, 1992a,b;Lin et al, 1992;Cáceres et al, 1995;Freiburghaus et al, 1996;Pietro et al, 2000;Ismail and Alam, 2001;Januario et al, 2002;Santos et al, 2003;Soares et al, 2003).…”

Bioactivity of the Alkaloids, Norharman and L-N-Methylcrotonosine/Linearisine

“…They are believed to be responsible for defence as well as the pesticidal, medicinal and allelopathic properties of plants (dos Santos et al, 2003;Hafiza et al, 2002;Amusan et al, 2000;Hostettmann and Marston, 1987;Kloos and McCullough, 1987;Youdeowei and Service, 1983). Alkaloids comprise the largest class of secondary plant substances (Harborne, 2012).…”