Immunological follow-up of hydatid cyst cases

Bulut, Vedat; Ilhan, Fulya; Yucel, Ahmet Ali; Önal, Süleyman; Ilhan, Yavuz Selim; Gödekmerdan, Ahmet

doi:10.1590/s0074-02762001000500015

Cited by 14 publications

(11 citation statements)

References 4 publications

(2 reference statements)

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“…In the present study, assessment of serum anti-hydatid antibodies using ELISA resulted in positive readings during the postoperative follow-up period, limiting its usefulness for postsurgical monitoring. Similarly, different immunoglobulin isotypes were detected 3 years after surgical removal of cysts in patients showing no evidence of remaining cysts (40) (41) .…”

Section: Discussionmentioning

confidence: 91%

Clinical and serological outcomes with different surgical approaches for human hepatic hydatidosis

Abdelraouf

El-Aal

Shoeib

et al. 2015

Rev. Soc. Bras. Med. Trop.

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Introduction: Hydatidosis is the result of infection with the larval stages of some species of the genus Echinococcus. Treatment approaches for hydatid cysts include the use of albendazole, surgery, and/or medico-surgical procedures. The choice of the therapeutic surgical approach depends on the cyst number and localization, surgeon expertise, and presence of complications. The present study aimed to compare the outcomes of the following therapeutic approaches for the treatment of hepatic hydatid cysts: pericystectomy; the puncture, aspiration, injection, and reaspiration (PAIR) technique; and the PAIR technique followed by deroofi ng, evacuation of cysts, and omentoplasty. Methods: The 54 patients were divided into 3 groups: Group I (14 patients) who underwent pericystectomy, Group II (23 patients) who underwent the PAIR technique, and Group III (17 patients) who underwent the PAIR technique followed by deroofi ng and omentoplasty. The diagnosis of hydatid cysts was based on serological testing using enzyme-linked immunosorbent assay, abdominal ultrasound, and parasitological examination of the cyst contents. Morbidity, mortality, length of hospital stay, recurrence, and postoperative complications were evaluated. Results: Postoperative bleeding, infection, and recurrence were reported in Groups I and II; Group III did not experience postoperative infection and had shorter hospital stays. Recurrence and postoperative complications did not occur in Group III. Conclusions: The partial surgical procedure with deroofi ng, evacuation of the cysts, and omentoplasty, as performed in the present study, is recommended as a safe and effective method for elimination of the entire parasite with minimal possibility for intra-peritoneal spillage.

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Section: Discussionmentioning

confidence: 91%

Clinical and serological outcomes with different surgical approaches for human hepatic hydatidosis

Abdelraouf

El-Aal

Shoeib

et al. 2015

Rev. Soc. Bras. Med. Trop.

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“…Generally, antibody titres increase upon relapse, but this does not always occur . Assays detecting specific antibody classes , and the use of several recombinant proteins (P29, 2B2t, HSP20, EgEF‐1β/δ) and change in band pattern on immunoblotting have been suggested to improve diagnostic evaluation of infection activity. Preliminary data from our group suggest that development of serodiagnostic tests for distinct use in diagnosis or follow‐up is possible , but they are still at the proof of concept stage.…”

Section: The Immune Response Applied To the Diagnosis Of Cementioning

confidence: 99%

The intermediate host immune response in cystic echinococcosis

Tamarozzi

Mariconti²,

Neumayr

et al. 2016

Parasite Immunology

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Cystic echinococcosis (CE) is a chronic, complex and neglected zoonotic infection. In most cases, CE cysts and the intermediate host co-habit for a long time in the absence of symptoms and elicit very little inflammation. However, the immune interplay between the parasite and the host is complex, encompassing effective parasite-killing immune mechanisms implemented by the host, which in turn are modulated by the parasite. The immune response to the parasite has been exploited for the diagnosis of the disease and for the development of an effective vaccine to use in the natural intermediate host, but the mechanisms of parasite killing and immunomodulation are still unknown. Here, we reviewed the immune effector mechanisms and the strategies of immune evasion in the intermediate host.

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“…In our work, anti hydatid antibodies assessment by ELISA technique detected positive readings in serum of the cases in the postoperative follow up period limiting its usefulness in postsurgical monitoring. Similarly, different immunoglobulins isotypes were detected 3 years after surgical removal of cysts in patients showing no evidences of remaining cysts [40,41].…”

Section: Discussionmentioning

confidence: 90%