Laryngeal Papillomatosis in an AIDS Patient

Oliveira, Ledy H. S.; Cavalcanti, Silvia Mb; Andrade, Denise D.; Fonseca, E Castellanos

doi:10.1590/s0074-02761998000600024

Cited by 1 publication

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“…6 Due to recurrent nature of HPV laryngeal papillomas, they are referred as recurrent respiratory papillomatosis. 7 HPV negative papillomatous lesions in the larynx are not frequent as majority of the lesions are tested positive. In our patient, the specimen tested negative for human papilloma virus.…”

Section: Discussionmentioning

confidence: 99%

Retroviral Disease and Smoking – A Sinister Combination causing Hyperkeratotic Laryngeal Papilloma

Bharathi

Rakesh

Unisa

et al. 2022

BJOHNS

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Introduction Otorhinolaryngologic manifestations account for almost 80% of the various manifestations of Human Immunodeficiency Virus (HIV) infection, of which Human Papilloma Virus (HPV) associated laryngeal papilloma and laryngeal malignancy are the most common pertaining to larynx. Case Report A 55year old male patient on Antiretroviral treatment since 10 years who was a chronic smoker, presented with difficulty in breathing and hoarseness of voice. Flexible laryngoscopy revealed a white, horny, wide based keratotic lesion completely covering rima glottidis resulting in obstruction of airway and stridor. Tracheostomy was done followed by endoscopic excision of the lesion. Histopathologic examination showed features of hyperkeratotic papilloma and lesion was tested negative for HPV. Discussion We report this case to emphasize on the differential diagnosis of laryngeal papillomatous lesion. A hyperkeratotic papilloma, with a dual aetiology of retroviral disease and smoking, presenting with stridor, the lesion being negative for HPV infection makes it uncommon from other laryngeal lesions.

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Section: Discussionmentioning

confidence: 99%