Detection of the human parvovirus B19 in a blood donor plasma in Rio de Janeiro

Human parvovirus B19 infection and hydrops fetalis in Rio de Janeiro, Brazil

“…This would be consistent with the seasonality described in Rio de Janeiro for exanthematic disease (Schatzmayr 1985). Two of the positive cases occurred during November and December 1988, coinciding with the finding by chance of a B19 infected blood donor (Cruz et al 1989). This supports the suggestion that 1988 was an epidemic year for B19 infection in Rio de Janeiro.…”

“…The probe was made from the 5.2 Kb Eco RI fragment excised from the B19/pGem-1 plasmid (Mori et al 1989). Diluted plasma from a viremic blood donor (Cruz et al 1989) and normal human serum were used as positive and negative controls.…”

Parvovirus B19 infections in state of Rio de Janeiro, Brasil: 526 sera analyzed by IgM-enzyme-linked immunosorbent assay and polymerase chain reaction

“…B19 antigen was also detected in the plasma of a healthy blood donor in Rio de Janeiro (Cruz et al 1989). Besides, an IgG antibody prevalence of 35% was demonstrated for children under five years, while almost 80% was reported in children aged from 11 to 15 years and 90% in individuals over 50 years old (Nascimento et al 1990).…”

Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises

“…Sickle cell disease is the most common chronic hemolytic anaemia in Brazil and one of the most important genetic diseases in this country 27 . We have studied the human parvovirus B19 circulation in Brazil since 1988, when we found an asymptomatic viremic blood donor in Rio de Janeiro 9 . Infection is widespread in Rio de Janeiro city where anti-B19 IgG antibodies were found in 73.7% of the sera collected during 1985 and 1986 25 .…”