Parasite-host interrelationships of Blastocrithidia Triatomae and triatomines

Schaub, Günter A.

doi:10.1590/s0074-02761988000500075

Cited by 9 publications

(8 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, the studies on interactions of insect trypanosomatids with their hosts are still incipient [7], [16]–[19], [35], [36]. The occurrence of horizontal transmission of L. wallacei by O. fasciatus was evident in the present study, corroborating previous data [6].…”

Section: Resultssupporting

confidence: 90%

“…Coprophagy among phytophagous and wood-feeding insects seems likely to have been positively selected throughout evolution, since this habit greatly facilitates the transmission of cellulose degrading gut microbiota between these insects [39]. Horizontal transmission by ingestion of parasites present in the insect feces, including cystic forms, has been extensively studied in the interaction between the trypanosomatid Blastocrithidia triatomae and the hematofagous insect Triatoma infestans , as well as other triatomines [27], [35], [36]. Along with cystic forms, live promastigote forms were observed in fresh feces, so we speculated that horizontal transmission takes place mostly by ingestion of these contaminated feces, which has already been observed for the trypanosomatid Crithidia bombi within a population of its natural host, bumblebees of the genus Bombus [21].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Transovum Transmission of Trypanosomatid Cysts in the Milkweed Bug, Oncopeltus fasciatus

Dias

Vasconcellos²,

Romeiro³

et al. 2014

PLoS ONE

View full text Add to dashboard Cite

Leptomonas wallacei is a trypanosomatid that develops promastigotes and cystic forms in the gut of the hemipteran insect Oncopeltus fasciatus. Insect trypanosomatids are thought to be solely transmitted from one host to another through the ingestion of parasite-contaminated feces. However, here we show that L. wallacei cysts present on the eggshells of eggs laid by O. fasciatus can also act as infective forms that are transmitted to the insect offspring. Newly hatched O. faciatus nymphs are parasite-free, but some of them become contaminated with L. wallacei after feeding on eggshell remnants. The present study is the first report of transovum transmission of a trypanosomatid, a process that may have a relevant role in parasite’s within-host population dynamics.

show abstract

Section: Resultssupporting

confidence: 90%

Section: Resultsmentioning

confidence: 99%

Transovum Transmission of Trypanosomatid Cysts in the Milkweed Bug, Oncopeltus fasciatus

Dias

Vasconcellos²,

Romeiro³

et al. 2014

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…They can only be distinguished by well-trained staff and sometimes require further molecular or biochemical characterizations (Schaub 2009). The homoxenous flagellate Blastocrithidia triatomae owed its discovery to extensive surveys of xenodiagnosis (Cerisola et al 1971;Schaub 1988b). When the BAYER company proved the efficiency of the first chemotherapy compound for Chagas disease, the nitrofuran Lampit ® , the treatment seemed to be ineffective in some cases.…”

Section: Disadvantages Of Xenodiagnosis Of Chagas Disease: False Posimentioning

confidence: 99%

Xenodiagnosis

Meiser¹,

Schaub²

2011

Nature Helps...

Self Cite

View full text Add to dashboard Cite

In xenodiagnosis, the vector of a pathogenic agent is infected to make identification of the parasite easier after a period of multiplications. This enables a diagnosis if the strain of the pathogen possesses a low virulence or if very low numbers of parasites occur in the blood, for example Trypanosoma cruzi in the chronic phase of Chagas disease. In 1914, 5 years after the discovery of T. cruzi in the triatomines, its blood-sucking vectors, these were used for the first time as a diagnostic tool of this disease. For many decades thereafter xenodiagnosis represented the golden standard. Meanwhile serological and molecular biological methods are preferably used for diagnosis today, but xenodiagnosis and in vitro cultivation are still the best methods for a proof of the living parasites or for the isolation of the flagellate. In this context, the different methodological variations and the disadvantages and advantages of xenodiagnosis are discussed in our review.

show abstract

“…The isolation of monoxenous trypanosomatids from bloodsucking insects has been reported on Triatoma infestans, Aedes vexans, Anopheles quadrimaculatus, and Culex pipiens (Novy et al 1907;Mezincescu 1908;Wallace and Johnson 1961;Cerisola et al 1971;Noguchi and Tilden 1926). Furthermore, some authors have observed pathogenic effects of monoxenic trypanosomatids on their host insect; such as Blastocrithidia triatomae on T. infestans, a main vector of Chagas' disease (Schaub 1988;Schaub et al 1988). This indicates that monoxenic trypanosomatids are potential agents for biological control strategies (Schaub 1988).…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, some authors have observed pathogenic effects of monoxenic trypanosomatids on their host insect; such as Blastocrithidia triatomae on T. infestans, a main vector of Chagas' disease (Schaub 1988;Schaub et al 1988). This indicates that monoxenic trypanosomatids are potential agents for biological control strategies (Schaub 1988). Studies involving the interaction of monoxenous trypanosomatids with hematophagous insects have acquired more importance because opportunistic infections of currently nonpathogenic trypanosomatids have been described in humans with immunodeficiency (Dedet et al 1995;Jiménez et al 1996;Pacheco et al 1998;Chicarro and Alvar 2003).…”

Section: Introductionmentioning

confidence: 99%

Colonization of Aedes aegypti midgut by the endosymbiont-bearing trypanosomatid Blastocrithidia culicis

et al. 2006

View full text Add to dashboard Cite

Monoxenous trypanosomatids inhabit invertebrate hosts throughout their life cycle. However, there have been cases of HIV-positive patients who have presented opportunistic infections caused by these protozoa, offering new perspectives to the study of interactions between monoxenics and hematophagous insect vectors. Some monoxenous trypanosomatids present a symbiotic bacterium in the cytoplasm, which seems to promote biochemical and morphological changes in the host trypanosomatids, such as alterations in plasma membrane carbohydrates and the reduction of the paraxial rod. In this work, we investigated the colonization of Aedes aegypti with Blastocrithidia culicis, an endosymbiont-bearing trypanosomatid. B. culicis remained in the insect digestive tract for 38 days after feeding. Optical microscopy analysis revealed an infection process characterized by a homogenous distribution of the trypanosomatid along the midgut epithelium; no preferential interaction of protozoa with any cell type was observed. Ultrastructural analysis showed that during the colonization process, trypanosomatids interacted mainly with midgut cells through their flagellum, which penetrates the microvilli preferentially near the tight junctions. Prolonged infections promoted insect midgut degradation, culminating with the arrival of protozoa in the hemocel. By demonstrating B. culicis colonization in a bloodsucking insect, we suggest that vector transmission of monoxenous trypanosomatids to vertebrate host may occur in nature.

show abstract

Parasite-host interrelationships of Blastocrithidia Triatomae and triatomines

Cited by 9 publications

References 0 publications

Transovum Transmission of Trypanosomatid Cysts in the Milkweed Bug, Oncopeltus fasciatus

Transovum Transmission of Trypanosomatid Cysts in the Milkweed Bug, Oncopeltus fasciatus

Xenodiagnosis

Colonization of Aedes aegypti midgut by the endosymbiont-bearing trypanosomatid Blastocrithidia culicis

Contact Info

Product

Resources

About