Da pesquiza de antijeno e de anticorpo pela fixação de complemento

Moses, Arthur

doi:10.1590/s0074-02761909000200005

Cited by 3 publications

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“…The MIOC began its publication in 1909, with 16 articles on varying subjects, e.g., amoeba, (29) diptera, (30,31,32) antibodies, antigens, (33) bacteria, (34) parasites, (35,36) smallpox, (37) tuberculosis. (38) The first MIOC issue also brought an article by Carlos Chagas on a new human Trypanosoma, (39) which would become a classic in the medical and biomedical literature, opening a line of research still in practice today at the IOC and that would become the predominant research topic disseminated by the MIOC.…”

Section: Discussionmentioning

confidence: 99%

The scientific publication of the Memórias do Instituto Oswaldo Cruz (1909-2020): a history of contribution to the biomedical sciences

Mota

Braga

Cabral

et al. 2022

Mem. Inst. Oswaldo Cruz

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BACKGROUNDThe Memórias do Instituto Oswaldo Cruz (MIOC) is one of the first scientific journals created in Brazil and currently one of the most important biomedical journals in South America. Knowledge of the main themes disseminated over time and its main contributors can contribute towards a better understanding of its trajectory and future.OBJECTIVES Map the journal's scientific publication between 1909 and 2020.METHODS Data from three scientific databases was combined, alongside bibliometrics and network analysis to analyse publication records between 1909 and 2020.FINDINGS Publications increased substantially since the 1980s. The main publishing organisations are Brazilian. Excluding Brazil, the main publishing countries are the USA, Argentina, and Colombia. During the entire investigated period, the main themes refer to Chagas disease, schistosomiasis, and Leishmaniasis. During some periods, publications followed disease outbreaks in Brazil (e.g., dengue fever and yellow fever).MAIN CONCLUSIONS Since its foundation in 1909, the MIOC has focused on infectious and parasitic diseases. The editorial changes implemented from the 1980s onwards led MIOC to a relevant growth concerning annual publications and its transformation into an important communication vehicle for researchers from several Brazilian organisations besides Fiocruz, as well as organisations from other countries, especially within Latin America.

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Section: Discussionmentioning

confidence: 99%

The scientific publication of the Memórias do Instituto Oswaldo Cruz (1909-2020): a history of contribution to the biomedical sciences

Mota

Braga

Cabral

et al. 2022

Mem. Inst. Oswaldo Cruz

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Lyssa

Lubinski¹,

Prausnitz²

1926

Ergebnisse Der Hygiene Bakteriologie Immunitätsforschung Und Experimentellen Therapie

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Studies in Anti-rabies Immunisation

Stuart

Krikorian

1929

J. Hyg.

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1. Statistical evidence and animal experiment have alike proved carbolised killed anti-rabies vaccine to be of undoubted efficacy in both pre-infectional and post-infectional treatment. Statistical evidence is furnished by the results of treatment of 90,000 patients, while experimental proof rests partly on the resistance shown by immunised animals to artificial infections with street virus, and partly on an estimation of degree and duration of rabicidal properties in their sera.2. The Bordet-Gengou reaction is of no value as a qualitative or quantitative test for the estimation of anti-rabies immunity.3. The efficacy of killed carbolised vaccine and probably of other antirabies vaccines is largely dependent on the concentration of the dosage and the period within which it is administered. Better results follow the giving of small doses over a number of days than the giving of larger doses over a shorter period.4. It is impossible to reduce below a certain limit the time over which the total quantity of vaccine ordinarily sufficient for complete immunisation can be usefully administered.5. The effect on rabbits of the subcutaneous injection of fresh-fixed virus is dependent on the quantity of virus introduced and on the duration of its period of administration. Few inoculations are more likely to cause death than several; repeated inoculations ordinarily confer immunity. Immunity thus acquired must have been produced within 11 or 12 days.

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Da pesquiza de antijeno e de anticorpo pela fixação de complemento

Cited by 3 publications

References 0 publications

The scientific publication of the Memórias do Instituto Oswaldo Cruz (1909-2020): a history of contribution to the biomedical sciences

The scientific publication of the Memórias do Instituto Oswaldo Cruz (1909-2020): a history of contribution to the biomedical sciences

Lyssa

Studies in Anti-rabies Immunisation

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