Deficiência de tiamina como causa de cor pulmonale reversível

Coelho, Liana Sousa; Hueb, João Carlos; Minicucci, Marcos F.; Azevedo, Paula S.; Paiva, Sérgio Alberto Rupp de; Zornoff, Leonardo A. M.

doi:10.1590/s0066-782x2008001300013

Cited by 21 publications

(8 citation statements)

References 5 publications

(10 reference statements)

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“…This extreme form of cardiac beriberi also known as Shoshin beriberi is not common. Recently some cases in adults have been reported from East Asia and some developed countries 6, 9. It is extremely rare in infants.…”

Section: Discussionmentioning

confidence: 99%

“…It has been appropriately designated as “a rapidly curable hemodynamic disaster” with an extremely high mortality if not treated early 5 . It is characterized by hypotension, tachycardia, and lactic acidosis 6, 7, 8. Severe pulmonary hypertension can develop due to an increased pulmonary arterial blood flow and elevated LV end-diastolic pressure 9 .…”

Section: Introductionmentioning

confidence: 99%

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Shoshin beriberi-thiamine responsive pulmonary hypertension in exclusively breastfed infants: A study from northern India

Bhat

Rather

Ahangar

et al. 2017

Indian Heart Journal

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Shoshin beriberi-thiamine responsive pulmonary hypertension in exclusively breastfed infants: A study from northern India

Bhat

Rather

Ahangar

et al. 2017

Indian Heart Journal

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“…Patients can also present with cardiomegaly, myocardial infarction with nonobstructive coronary arteries, coronary vasospasm or pulmonary hypertension [6].…”

Section: Discussionmentioning

confidence: 99%

Wernicke encephalopathy and beriberi disease presenting as STEMI-equivalent

Carvalho

Proença

Pinto

et al. 2023

Monaldi Arch Chest Dis

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Thiamine deficiency is commonly associated with malnutrition, alcoholism and bariatric surgery. Thiamine deficiency can manifest in different ways, especially in developing countries: as peripheric neuropathy, as Wernicke encephalopathy or as beriberi disease. The authors present the case of a 72-year-old male, with a hiatal hernia that led to thiamine deficiency due to malnutrition. The initial clinical manifestation was an ST-elevation myocardial infarct equivalent, an ECG with a shark-fin pattern that evolved to a Wellens type B pattern. The patient evolved with severe altered mental status. A Wernicke encephalopathy diagnosis was confirmed by MRI; the patient was medicated with high-dose thiamine, with quick recovery, both neurologic and cardiac. The clinical history and response to treatment confirm the diagnosis of Wernicke encephalopathy and beriberi disease.

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“…Adicionalmente, houve resposta clínica imediata com a reposição de tiamina. Assim, apesar de não termos feito a dosagem da atividade da transquetolase eritrocítica, o beribéri tornou-se a hipótese mais provável para nosso paciente (COELHO, et al, 2007).…”

Section: Discussionunclassified

Relato De Caso: Deficiência De Tiamina Como Causa De Descompensação Cardíaca

Rodrigues¹,

Carvalho²,

Cirqueira³

et al. 2017

Acta Biomed.Bras.

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RESUMOO beribéri é uma doença causada pela falta de vitamina B1 (tiamina) no organismo, decorrente de várias causas, que pode gerar alterações nervosas, cerebrais e cardíacas. Objetivo: relatar o caso de uma paciente com insuficiência cardíaca, que obteve regressão dos sinais e sintomas após medicação com tiamina, corroborando na literatura descrita sobre o tema, pela raridade do caso. Metodologia: relato de caso. Resultados: a administração de tiamina por via parenteral, resultou em melhora parcial do quadro clínico após 3 dias e melhora total do quadro 5 dias após o uso de tiamina, comprovada por novo ecocardiograma. Conclusão: manifestações cardiovasculares (beribéri úmido) da deficiência de tiamina são raras e sua forma extrema, de Shoshin, é rapidamente fatal a menos que a terapia específica seja dada. O tratamento consiste na administração de tiamina, com melhora clínica rápida após sua suplementação.Palavras chave: Beribéri; Deficiência de tiamina; Insuficiência cardíaca. ABSTRACTBeriberi is a disease caused by a lack of vitamin B1 (thiamine) in the body, due to several causes, which can lead to nervous, brain and heart changes. Objective: to report the case of a patient with heart failure, who obtained regression of the signs and symptoms after thiamine medication, corroborating in the literature described on the subject, the rarity of the case. Methodology: case report. Results: administration of thiamine parenterally resulted in partial improvement of the clinical picture after 3 days and total improvement of the picture 5 days after the use of thiamine, confirmed by a new echocardiogram. Conclusion: cardiovascular (wet beriberi) manifestations of thiamine deficiency are rare and its extreme form, Shoshin's, is rapidly fatal unless specific therapy is given. Treatment consists of the administration of thiamine, with rapid clinical improvement after its supplementation.

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Deficiência de tiamina como causa de cor pulmonale reversível

Cited by 21 publications

References 5 publications

Shoshin beriberi-thiamine responsive pulmonary hypertension in exclusively breastfed infants: A study from northern India

Shoshin beriberi-thiamine responsive pulmonary hypertension in exclusively breastfed infants: A study from northern India

Wernicke encephalopathy and beriberi disease presenting as STEMI-equivalent

Relato De Caso: Deficiência De Tiamina Como Causa De Descompensação Cardíaca

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