2006
DOI: 10.1590/s0066-782x2006000200005
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Abstract: The heart failure (HF) reported by MI rats with > 40% MI at the end of the healing period is not myocardial function dependent. Chamber structural changes and lower population of myocites should base VD and HF.

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Cited by 17 publications
(4 citation statements)
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“…In the early stages, the impaired contractility of the remaining myocardium does not contribute to ventricular dysfunction. Rats examined three weeks after arterial occlusion presented clear signs of ventricular dysfunction, although no impairment of inotropism was identified in the non-necrotic myocardium 11,24 .…”
Section: Left Ventricle Diastolic Volume (Ml)mentioning
confidence: 96%
“…In the early stages, the impaired contractility of the remaining myocardium does not contribute to ventricular dysfunction. Rats examined three weeks after arterial occlusion presented clear signs of ventricular dysfunction, although no impairment of inotropism was identified in the non-necrotic myocardium 11,24 .…”
Section: Left Ventricle Diastolic Volume (Ml)mentioning
confidence: 96%
“…The ejection fraction (EF) was calculated by the cube method (LVEF=(diastolic ventricular volume) 3 −(systolic ventricular volume) 3 /(diastolic ventricular volume) 3 ×100), and the LV fractional shortening (FS) was calculated as diastolic ventricular diameter−systolic ventricular diameter)/diastolic ventricular diameter [25]. The extent of infarction (MI %), assessed by measuring the length of the akinetic and/or hypokinetic segments (RAH) of the ventricular walls, is expressed as a percentage of the total perimeter of the endocardium (PE) in three transverse sections of the LV (the edges of the mitral valve leaflets, papillary muscles and apical), using the formula: MI %=(RAH/PE)×100 [26]. The images were captured by an operator who was blinded to the study groups.…”
Section: Echocardiogrammentioning
confidence: 99%
“…28 The arch corresponding to the cardiac segments with infarction was measured at end-diastole in the 3 planes. 28–30 LV systolic output (mL) and cardiac output (mL/min) were calculated as previously described. 30…”
Section: Methodsmentioning
confidence: 99%