Uso de digital em idosos admitidos em unidade de geriatria de um hospital geral

Cunha, Ulisses Gabriel de Vasconcelos; Barbosa, Maira Tonidandel; Paradela, Emylucy Martins Paiva; Carvalho, Flávio Gomes

doi:10.1590/s0066-782x1998001100009

Cited by 6 publications

(5 citation statements)

References 14 publications

(16 reference statements)

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“…However, cardiac function was tested at rest under anesthesia. Endurance exercise training enhances functional capacity, improves sympathetic system control, and increases cardiac output during exercise [10]. It has been described that heart rate or cardiac output was unchanged in trained or untrained subjects at rest, which supports our results [15].…”

Section: (N = 8) Digo (N = 8) T (N = 8) Tdigo (N = 8)supporting

confidence: 91%

Digoxin Induces Cardiac Hypertrophy Without Negative Effects on Cardiac Function and Physical Performance in Trained Normotensive Rats

et al. 2017

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Cardiotonic drugs and exercise training promote cardiac inotropic effects, which may affect training-induced cardiac adaptations. This study investigated the effects of long-term administration of digoxin on heart structure and function, and physical performance of rats submitted to high-intensity interval training (HIIT). Male Wistar rats, 60 days old, were divided into control (C), digoxin (DIGO), trained (T), and trained with digoxin (TDIGO). Digoxin was administered by gavage (30 µg/kg/day) for 75 days. The HIIT program consisted of treadmill running 60 min/day (8 min at 80% of the maximum speed (MS) and 2 min at 20% of the MS), 5 days per week during 60 days. The main cardiac parameters were evaluated by echocardiograph and cardiomyocyte area was determined by histology. There were no group x time effects of digoxin, HIIT or interactions (digoxin and HIIT) on functional echocardiographic parameters (heart rate; ejection fraction) or in the maximum exercise test. There was a group x time interaction, as evidenced by observed cardiac hypertrophy in the TDIGO group evaluated by ratio of left ventricle weight to body weight (p<0.002) and cardiomyocyte area (p<0.000002). Long-term administration of digoxin promoted cardiac hypertrophy without affecting cardiac function and physical performance in rats submitted to HIIT.

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Section: (N = 8) Digo (N = 8) T (N = 8) Tdigo (N = 8)supporting

confidence: 91%

Digoxin Induces Cardiac Hypertrophy Without Negative Effects on Cardiac Function and Physical Performance in Trained Normotensive Rats

et al. 2017

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“…The association between the use of digitalics and risk of developing tachycardia, and from this, increased chance of death, also corroborates data in the literature guiding the judicious use of digitalics. Cunha et al 25 found that in 52.7% of the studied patients, the prescription of digitalics was inadequate. The evaluation of ejection fraction is required as well as the optimization of treatment for the correct prescription of digitalics.…”

Section: Discussionmentioning

confidence: 95%

Epidemiological and assistance care profile of patients with heart failure in a regional reference municipality

Graciano¹,

Lago²,

Júnior³

et al. 2015

Revista Médica De Minas Gerais

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Introduction: heart failure is a crippling disease that reduces the quality of life; therefore, it is a serious public health problem. Objectives: to analyze the epidemiological and assistance care profile of heart failure patients admitted to a regional reference hospital. Statistically correlate clinical signs to diagnostic criteria and admissions to primary care services. To verify consistency between the treatment used and heart failure guidelines. Patients and methods: this was a prevalence, cross-sectional, and an exploratory study conducted through the reading of medical charts from a regional reference hospital from patients whose cause for hospitalization was heart failure in 2010. The data were analyzed in the Epi-Info 3.5 software. Frequency analysis and Odds Ratio (OR) with 95% confidence interval were calculated taking into account the P-value calculated through the Fisher's exact test. The project was approved by the University Ethics Committee (Protocol 159/2011). Results: 54 medical records were analyzed; 81% of patients had access to a primary care unit in the area of their residence. Dyslipidemia was associated with the highest number of hospitalizations (OR = 16/P = 0.034). The primary etiology of heart failure was systemic hypertensive heart disease (72.2%). The main risk factors found were hypertension (66.7%), smoking (48.1%), diabetes mellitus (44.4%), and dyslipidemia (40.7%). Out of the heart failure diagnoses, 68.52% could have been made from the Framingham criteria. Conclusions: permanent education programs are needed for addressing heart failure risk factors, evaluation and adherence to treatment, and active search for cases in the primary care as well as diagnosis of heart failure and its proper management.

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“…Quanto aos digitálicos, estudo entre idosos hospitalizados identificou que 27,6% faziam uso, com indicação avaliada como inadequada em 52,7% dos casos 34 . Mesmo considerando serem populações com características diferentes, tais dados são divergentes dos encontrados no presente estudo, uma vez que apenas 9 (3%) idosos utilizam digitálicos.…”

Section: Metodologiaunclassified

Caracterização do uso de medicamentos entre idosos de uma unidade do Programa Saúde da Família

et al. 2008

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IntroduçãoNos últimos decênios tem aumentado a preocupação com melhoria das condições de vida na velhice. No Brasil, a população idosa, em 2002, perfazia um total de 14,1 milhões de pessoas e projetava-se para 2025 um total de 33,4 milhões, sendo que entre 1950 e 2025 a população idosa terá crescido 16 vezes contra 5 vezes a população total 1 . Destaca-se na população idosa o aumento de pessoas com oitenta anos ou mais, sendo essa a faixa etária de maior crescimento, tanto nos países desenvolvidos como nos países em desenvolvimento 2 .Juntamente com as modificações da estrutura etária da população, constatam-se mudanças epidemiológicas, com a substituição das causas principais de morte por doenças parasitárias, de caráter agudo, pelas doenças crônico-degenerativas (diabetes, acidente vascular cerebral, neoplasias, hipertensão arterial, demência senil e outras), que se transformam em problemas de longa duração e envolvem, para atendimento adequado, grande quantidade de recursos materiais e humanos 3 .Por conviver com problemas crônicos de saú-de, os idosos utilizam com freqüência os serviços de saúde e são consumidores de grande número de medicamentos 4 , que embora necessários em muitas ocasiões, quando mal utilizados podem desencadear complicações sérias para a saúde e aumento dos custos individuais e governamen-ARTIGO ARTICLE

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Uso de digital em idosos admitidos em unidade de geriatria de um hospital geral

Cited by 6 publications

References 14 publications

Digoxin Induces Cardiac Hypertrophy Without Negative Effects on Cardiac Function and Physical Performance in Trained Normotensive Rats

Digoxin Induces Cardiac Hypertrophy Without Negative Effects on Cardiac Function and Physical Performance in Trained Normotensive Rats

Epidemiological and assistance care profile of patients with heart failure in a regional reference municipality

Caracterização do uso de medicamentos entre idosos de uma unidade do Programa Saúde da Família

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