Epidemiological study on leishmaniasis in an area of environmental tourism and ecotourism, State of Mato Grosso do Sul, 2006-2007

Andrade, Ana Rachel Oliveira de; Nunes, Vânia Lúcia Brandão; Galati, Eunice Aparecida Bianchi; Arruda, Carla Cardozo Pinto de; Santos, Mirella Ferreira da Cunha; Rocca, Maria Elizabeth Gizi; Aquino, Ricardo Braga

doi:10.1590/s0037-86822009000500003

Cited by 29 publications

(33 citation statements)

References 15 publications

(9 reference statements)

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“…Anti-Leishmania spp. antibodies in the states of Mato Grosso and Mato Grosso do Sul have been reported by other researchers, with frequencies higher than that observed in this work and according to the particular characteristics of each region under study (NUNES et al, 2001;CORTADA et al, 2004;ANDRADE et al, 2009;ALMEIDA et al, 2012;SOUSA et al, 2013;BRITO et al, 2014). This may be related to the opportunist feeding behavior of the vector.…”

Section: Discussioncontrasting

confidence: 48%

Rural area of the Brazilian Pantanal wetlands associated with the occurrence of anti-<i>Leishmania</i> spp. antibodies in dogs

Melo

Costa

Miyazaki

et al. 2017

Braz. J. Vet. Res. Anim. Sci.

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An evaluation was made of the presence of anti-Leishmania infantum chagasi antibodies in domestic dogs from the urban and rural areas of Brazil's Pantanal wetland region using serological techniques. A total of 429 dogs were sampled in three areas of the Pantanal biome, including the municipalities of Poconé, Santo Antônio de Leverger, and Barão de Melgaço, in the state of Mato Grosso, and in the municipality of Corumbá, in the state of Mato Grosso do Sul. The immunofluorescence assay (IFA) was used to detect antibodies (cut-off point 40) using Leishmania infantum chagasi antigen. Because of the possibility of cross-reactivity between species of the genus Leishmania, samples that were positive in the IFA against L. infantum chagasi were also tested by IFA in the same conditions, using L. amazonensis and L. braziliensis antigens. IFA-positive samples to L. infantum chagasi were also evaluated using Enzyme-Linked Immunosorbent Assay (ELISA). The results showed the presence of antibodies against L. infantum chagasi in 23 (5.36%; 95% CI: 3.50%-8.05%) dogs and at least one seroreactive dog was found in each of the municipalities evaluated in this study. Antibody titers ranged from 40 to 5,120, and all IFA positive samples were positive in the ELISA. Among the 23 positive dogs, nine were also were seroreactive for L. amazonensis and L. braziliensis antigens. The occurrence of anti-L. infantum chagasi antibodies in dogs was higher in rural areas (7.06%) than in urban areas (2.50%) (P < 0.05). Based on this study, we concluded that dogs from rural areas of the Pantanal wetlands were in contact with Leishmania species, which is relevant information given their importance to public health. Keywords: Dog. Leishmania spp. Antibodies. IFA. ELISA. Pantanal. ResumoNeste trabalho foi realizada uma avaliação sobre a presença de anticorpos anti-Leishmania infantum chagasi em cães domésticos das áreas urbanas e rurais da região do Pantanal brasileiro usando técnicas sorológicas. Um total de 429 cães foram amostrados em três áreas do bioma do Pantanal, incluindo os municípios de Poconé, Santo Antônio de Leverger e Barão de Melgaço, em Mato Grosso, e o município de Corumbá, em Mato Grosso do Sul. A reação de imunofluorescência indireta (RIFI) foi utilizada para detectar anticorpos (ponto de corte de 40) de Leishmania infantum chagasi como antígeno. Devido à possibilidade de reação cruzada entre as espécies do gênero Leishmania, as amostras positivas na RIFI para L. infantum chagasi foram também avaliadas na RIFI utilizando L. amazonensis e L. braziliensis como antígenos. As amostras positivas na RIFI para L. infantum chagasi foram avaliadas utilizando o ensaio de imunoadsorção ligado à enzima (ELISA). Os resultados mostraram a presença de anticorpos contra L. infantum chagasi em 23 (5,36%; IC 95%: 3,50% -8,05%) cães e pelo menos um cão soro-reativo foi encontrado em todos os municípios avaliados neste estudo. Os títulos de anticorpos variaram de 40 a 5.120 e todas as amostras positivas na RIFI foram positivas no ELISA. Entre...

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Section: Discussioncontrasting

confidence: 48%

Rural area of the Brazilian Pantanal wetlands associated with the occurrence of anti-<i>Leishmania</i> spp. antibodies in dogs

Melo

Costa

Miyazaki

et al. 2017

Braz. J. Vet. Res. Anim. Sci.

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“…Cross-reactivity between this antigen and other infectious agents has been demonstrated in several studies (VEXENAT et al, 1996;FERREIRA et al, 2007;ANDRADE et al, 2009), particularly for trypanosomes (FERREIRA et al, 2007).…”

Section: Discussionmentioning

confidence: 91%

“…This occurs because different pathogens present similar L. major-like epitope features, especially for closely related species (ANDRADE et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Antibodies to Leishmania spp. in domestic felines

Oliveira

Paiz

Menozzi

et al. 2015

Rev. Bras. Parasitol. Vet.

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Leishmaniasis is a vector-borne zoonotic disease caused by protozoa in the genus Leishmania, typical of rural and peri-urban environments. The causative agent of American visceral leishmaniasis is Leishmania (Leishmania) infantum chagasi and the main insect vector in Brazil is Lutzomyia longipalpis. Dogs (Canis familiaris) are important in the transmission of the disease, as a reservoir closely related to humans and an infection source for phlebotomine vectors. Since 1990, an increasing number of feline leishmaniasis cases have been reported, suggesting that domestic cats (Felis catus) might be involved in the epidemiology of the disease. The present study analyzed the prevalence of anti-Leishmania spp. antibodies in naturally infected domestic cats from various neighborhoods in the municipality of Belém, Pará, Brazil, using the indirect immunofluorescence assay (IFA) and the direct agglutination test (DAT). Among the 443 samples tested, 18 (4.06%) presented positive reactions in the IFA. The observed titers were 40 IU in 4.97% of the samples and 80 IU in 0.90%. In the DAT test, positive results were found in 25 (5.64%) of the samples. The observed titers were also 40 IU (4.97%) and 80 IU (0.68%). The agreement rate between the two tests was considered low (Kappa coefficient = 0.10).Keywords: Indirect immunofluorescence assay, direct agglutination test, leishmaniasis, cats. ResumoAs leishmanioses são zoonoses vetoriais causadas por protozoários do gênero Leishmania, características de ambientes rurais e periurbanos. A leishmaniose visceral americana (LVA) é causada pela Leishmania (Leishmania) infantum chagasi, cujo principal vetor no Brasil é Lutzomyia longipalpis. O cão (Canis familiaris) possui papel ativo na transmissão da doença, pois é um reservatório muito próximo do humano e uma fonte de infecção para o flebotomíneo. O aumento do número de casos de leishmaniose felina, descritos na literatura a partir de 1990, sugere Leishmaniasis is a vector-borne zoonotic disease caused by protozoa of the genus Leishmania, Kinetoplastida order, Trypanosomatidae family, and transmitted by phlebotomine species, causing tegumental and visceral injuries (ROSA, 2009). In the parasitic life cycle, promastigotes are found in the vector and amastigotes are found in the infected host tissues (BANETH, 2006). Leishmaniasis is typical of rural and peri-urban environments. Domestic and wild mammals can be infected; humans are considered accidental hosts of the protozoa (CURI et al., 2006).The dog (Canis familiaris) has an active role in the transmission of the disease as an asymptomatic reservoir that is closely related to humans and an infection source to phlebotomine vectors (COURTENAY et al., 2002).American visceral leishmaniasis is caused by Leishmania (Leishmania) infantum chagasi, and is a serious public health problem in Brazil owing to the wide geographical distribution v. 24, n. 4, out.-dez. 2015 465 Leishmania spp. in cats of the disease, high incidence, and the ability to lead to a severe clinical form that ...

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“…In Brazil, about 235 species have been reported 9 , 10 , 11 and 66 of these were registered in Mato Grosso do Sul 9 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 .…”

Section: Introductionmentioning

confidence: 99%

Sand Flies (Diptera: Psychodidae) in an Endemic Area of Leishmaniasis in Aquidauana Municipality, Pantanal of Mato Grosso Do Sul , Brazil

Figueiredo

Santos

Casaril

et al. 2016

Rev. Inst. Med. trop. S. Paulo

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SUMMARYThe Aquidauana municipality is considered an endemic area of leishmaniasis and an important tourist site in Mato Grosso do Sul State. The aim of this study was to investigate the sand fly fauna in the city of Aquidauana. Captures were carried out twice a month, from April 2012 to March 2014 with automatic light traps and active aspiration, in the peridomicile and domicile of six residences. A total of 9,338 specimens were collected, 3,179 and 6,159 using light traps and active aspiration, respectively. The fauna consisted of: Brumptomyia brumpti, Evandromyia aldafalcaoae, Ev. evandroi, Ev. lenti, Ev. orcyi, Ev. sallesi, Ev. termitophila, Ev. walkeri, Lutzomyia longipalpis and Psathyromyia bigeniculata. The most abundant species captured was Lutzomyia longipalpis, present in all the ecotopes, predominantly in peridomicile areas, and mainly males. Leishmania DNA was not detected in the insects. It was observed the abundance of the sand fly fauna in the region, as well as the high frequency of Lu. longipalpis, the main vector of L. infantum. The results of this study show the need to increase the monitoring and more effective control measures. It is noteworthy that the studied region presents several activities related to tourism and recreation, increasing the risk of transmission of leishmaniasis to this particular human population.

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Epidemiological study on leishmaniasis in an area of environmental tourism and ecotourism, State of Mato Grosso do Sul, 2006-2007

Cited by 29 publications

References 15 publications

Rural area of the Brazilian Pantanal wetlands associated with the occurrence of anti-<i>Leishmania</i> spp. antibodies in dogs

Rural area of the Brazilian Pantanal wetlands associated with the occurrence of anti-<i>Leishmania</i> spp. antibodies in dogs

Antibodies to Leishmania spp. in domestic felines

Sand Flies (Diptera: Psychodidae) in an Endemic Area of Leishmaniasis in Aquidauana Municipality, Pantanal of Mato Grosso Do Sul , Brazil

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