Malaria outbreaks in a non-endemic area of Brazil, 2005

Limongi, Jean Ezequiel; Chaves, Kátia Maria; Paula, Márcia Beatriz Cardoso de; Costa, Fabíola Corrêa da; Silva, Alcides de Assis e; Lopes, Íris de Sousa; Neto, Adalberto de Albuquerque Pajuaba; Sales, José Maria; Rodrigues, Fernando; Resende, Maria Angélica Montes; Ferreira, Marcelo Simão

doi:10.1590/s0037-86822008000300002

Cited by 18 publications

(12 citation statements)

References 5 publications

(2 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Relapses are dangerous because of their morbidity and risk of reintroducing malaria to areas where mosquito vectors are still present [39]. The occurrence of 12.6% P. vivax relapses that we found is lower that what was previously observed in other studies of imported malaria in Brazil [40,41], but the lack of monitoring for a cure after a first bout of treatment and distinct study methods might account for this difference.…”

Section: Discussioncontrasting

confidence: 75%

Imported malaria in a non-endemic area: the experience of the university of Campinas hospital in the Brazilian Southeast

Dos-Santos

Angerami

Castiñeiras

et al. 2014

Malar J

View full text Add to dashboard Cite

BackgroundAlthough malaria in Brazil almost exclusively occurs within the boundaries of the Amazon Region, some concerns are raised regarding imported malaria to non-endemic areas of the country, notably increased incidence of complications due to delayed diagnoses. However, although imported malaria in Brazil represents a major health problem, only a few studies have addressed this subject.MethodsA retrospective case series is presented in which 263 medical charts were analysed to investigate the clinical and epidemiological characterization of malaria cases that were diagnosed and treated at Hospital & Clinics, State University of Campinas between 1998 and 2011.ResultsAmongst all medical charts analysed, 224 patients had a parasitological confirmed diagnosis of malaria. Plasmodium vivax and Plasmodium falciparum were responsible for 67% and 30% of the infections, respectively. The majority of patients were male (83%) of a productive age (median, 37 years old). Importantly, severe complications did not differ significantly between P. vivax (14 cases, 9%) and P. falciparum (7 cases, 10%) infections.ConclusionsSevere malaria cases were frequent among imported cases in Brazil outside of the Amazon area. The findings reinforce the idea that P. vivax infections in Brazil are not benign, regardless the endemicity of the area studied. Moreover, as the hospital is located in a privileged site, it could be used for future studies of malaria relapses and primaquine resistance mechanisms. Finally, based on the volume of cases treated and the secondary complications, referral malaria services are needed in the non-endemic areas of Brazil for a rapid and efficient and treatment.

show abstract

Section: Discussioncontrasting

confidence: 75%

Imported malaria in a non-endemic area: the experience of the university of Campinas hospital in the Brazilian Southeast

Dos-Santos

Angerami

Castiñeiras

et al. 2014

Malar J

View full text Add to dashboard Cite

show abstract

“…In MG, Chaves et al. (1995) observed 471 autochthonous cases between 1980-1992, whereas Limongi et al (2008) diagnosed only one case in the same state in 2005. In PR, 851 cases of malaria were notified between 1992-2003 (Falavigna-Guilherme et al 2005), whereas 65 autochthonous cases occurred from 2001-2004 in ES (Cerutti Jr et al 2007).…”

Section: Discussionmentioning

confidence: 99%

Malaria in the state of Rio de Janeiro, Brazil, an Atlantic Forest area: an assessment using the health surveillance service

Miguel¹,

Peiter²,

Albuquerque³

et al. 2014

Mem. Inst. Oswaldo Cruz

View full text Add to dashboard Cite

The lethality of malaria in the extra-Amazonian region is more than 70 times higher than in Amazonia itself. Recently, several studies have shown that autochthonous malaria is not a rare event in the Brazilian southeastern states in the Atlantic Forest biome. Information about autochthonous malaria in the state of Rio de Janeiro (RJ) is scarce. This study aims to assess malaria cases reported to the Health Surveillance System of the State of Rio de Janeiro between 2000-2010. An average of 90 cases per year had parasitological malaria confirmation by thick smear. The number of malaria notifications due to Plasmodium falciparum increased over time. Imported cases reported during the period studied were spread among 51% of the municipalities (counties) of the state. Only 35 cases (4.3%) were autochthonous, which represents an average of 3.8 new cases per year. Eleven municipalities reported autochthonous cases; within these, six could be characterised as areas of residual or new foci of malaria from the Atlantic Forest system. The other 28 municipalities could become receptive for transmission reintroduction. Cases occurred during all periods of the year, but 62.9% of cases were in the first semester of each year. Assessing vulnerability and receptivity conditions and vector ecology is imperative to establish the real risk of malaria reintroduction in RJ.

show abstract

“…The introduction of new foci of malaria transmission in the forest and surrounding villages following gametocyte introduction by gold miners is not unusual. Indeed, in Brazil, malaria outbreaks generated by the arrival of gold prospectors coming from endemic areas were described most recently in Monte Alegre de Minas (south east region in the state of Minas Gerais), 14 and in the early 1990s in Mato Grosso. 15 As for individual vector prevention, bednets were used by 79% of the subjects among which 51% were insecticidetreated nets (ITN).…”

Section: Discussionmentioning

confidence: 99%

“…An epidemiological investigation was carried out from January [14][15][16]2009. This retrospective cohort study was based on the inhabitants of Saü l and surrounding areas present during the 3-day survey.…”

Section: Methodsmentioning

confidence: 99%

Investigation of a Sudden Malaria Outbreak in the Isolated Amazonian Village of Saül, French Guiana, January–April 2009

Berger¹,

Flamand²,

Musset³

et al. 2012

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Abstract. Malaria is endemic in French Guiana. Plasmodium falciparum and Plasmodium vivax are the predominant species responsible and Anopheles darlingi is described as the major vector. In mid-August 2008, an increase in malaria incidence was observed in Saü l. A retrospective cohort survey was performed. In vitro susceptibility profiles to antimalarials were determined on P. falciparum isolates. Collections of mosquitoes were organized. The malaria attack rate reached 70.6/100. The risk of malaria increased for people between 40 and 49 years of age, living in a house not subjected to a recent indoor residual insecticide spraying or staying overnight in the surrounding forest. All isolates were susceptible. Anopheles darlingi females and larvae were collected in the village suggesting a local transmission. Our results strongly support a role of illegal mining activities in the emergence of new foci of malaria. Therefore, public health authorities should define policies to fight malaria at a transborder level.

show abstract

Malaria outbreaks in a non-endemic area of Brazil, 2005

Cited by 18 publications

References 5 publications

Imported malaria in a non-endemic area: the experience of the university of Campinas hospital in the Brazilian Southeast

Imported malaria in a non-endemic area: the experience of the university of Campinas hospital in the Brazilian Southeast

Malaria in the state of Rio de Janeiro, Brazil, an Atlantic Forest area: an assessment using the health surveillance service

Investigation of a Sudden Malaria Outbreak in the Isolated Amazonian Village of Saül, French Guiana, January–April 2009

Contact Info

Product

Resources

About