Eventos adversos após vacinação contra influenza em idosos, Distrito de Campinas, SP, 2000

Abstract

Adverse reactions associated with vaccines are poorly documented in Brazil. The aim of this article was to identify the incidence of adverse effects to the influenza vaccine in the elderly of Campinas district, SP. A questionnaire was applied to a random systematic sample of people over 60 years of age (n = 206), participating in the Brazilian Vaccination Campaign during 2000. Temporal link was taken into account for general and local symptoms after vaccine. One or more symptoms were reported by 20.48% (CI 14.87-25.88) and local pain was the most frequent complaint 12.62% (CI 8.09 -17.15). A multi-regression logistic model was adjusted, considering any adverse effects after exposure as the dependent variable. The independent variable associated with adverse effects was female gender (OR = 5.89 and CI 2.08-16.68). This study reaffirms the low reactogenicity of influenza vaccine.

Influenza vaccination in non-institutionalized elderly: a population-based study in a medium-sized city in Southern Brazil

“…However, the prevalence of adverse events in the current study is consistent with the scientific literature as a whole, which also shows low prevalence of such events 23,28,31,32,33 . One Brazilian study identified pain at the vaccination site as the most frequent event (12.6%), followed by flu-like symptoms (7.8%).…”

“…One Brazilian study identified pain at the vaccination site as the most frequent event (12.6%), followed by flu-like symptoms (7.8%). However, in the current study the subjects were asked (with a closed question) whether they had experienced any symptoms like fever, pain at the vaccination site, and others 31 . Lack of reports of pain in this study may have occurred due to difficulty by the elderly in recalling the symptom, or because neither the elderly nor the mass media appeared to consider it important.…”

Situação vacinal e associação com a qualidade de vida, a funcionalidade e a motivação para o autocuidado em idosos

“…A higher percentage of female elderly (71.3%) was observed in the present study, similar to what was found by some authors (6,15) . In terms of the mean age of the participants, it was 70.30 years (standard deviation of +-7.62), which agrees with another study on the theme (6) .…”

“…The population studied has some similar characteristics to the population of other studies on the theme, regarding gender, age and vaccination status (4,6,13,14,15,16,17) . A higher percentage of female elderly (71.3%) was observed in the present study, similar to what was found by some authors (6,15) .…”

“…Frequently, symptoms, not always actually associated with vaccines, are attributed to immunization. Studies on the perception and representation of symptoms after vaccination may explain part of the reasons for low vaccination coverage and contribute to more specific educational interventions (6) . The influenza vaccine brings countless benefits to the elderly, given it provides high protection against frequent complications associated with the flu, which are responsible for hospitalization and deaths.…”