Mucosal leishmaniasis

Lambertucci, José Roberto; Coulaud, René; Silva, Luciana Cristina dos Santos

doi:10.1590/s0037-86822003000200017

Cited by 3 publications

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“…Diagnostic delays, which mean time in the present study was of six years, could be justified by the fact that the patients did not seek medical care. Nonetheless, since chronic nasal obstruction is the complaint which has a direct impact on the quality of life and the work capacity of the individual, it is improbable that such delay has been caused by a delay in seeking medical care 8 . In fact, LM patients report having been treated for chronic rhinitis during long periods of time, without a definitive etiological diagnosis 6 .…”

Section: Discussionmentioning

confidence: 99%

Mucocutaneous Leishmaniasis: clinical markers in presumptive diagnosis

Diniz¹,

Costa²,

Gonçalves³

2011

Braz. j. otorhinolaryngol. (Impr.)

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Mucocut aneous Leishmaniasis (ML) can lead to serious sequela; however, early diagnosis can prevent complications. Aim:To evaluate clinical markers for the early diagnosis of ML. Materials and Methods:A series study of 21 cases of ML, which were evaluated through clinical interview, nasal endoscopy, biopsy and the Montenegro test.Results: A skin scar and previous diagnosis of cutaneous leishmaniasis (CL) were reported in 8(38%) patients, and 13(62%) of them denied having had previous CL and had no scar. Nasal/oral symptom onset until the ML diagnosis varied from 5 months to 20 years, mean value of 6 years. In the Montenegro test, the average size of the papule was 14.5 mm, which did not correlate with disease duration (p=0.87). The nose was the most often involved site and the extension of the injured mucosa did not correlate with disease duration. The parasite was found in 2 (9.52%) biopsy specimens.Conclusions: ML diagnosis was late. Finding the parasite in the mucosa, cutaneous scar and/ or previous diagnosis of CL were not clinical markers for ML. ML diagnosis must be based on the Montenegro test, chronic nasal and/or oral discharge and histological findings ruling out other granulomatous diseases. Braz J Otorhinolaryngol. 2011;77(3):380-4. ORIGINAL ARTICLE BJORL

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Section: Discussionmentioning

confidence: 99%

Mucocutaneous Leishmaniasis: clinical markers in presumptive diagnosis

Diniz¹,

Costa²,

Gonçalves³

2011

Braz. j. otorhinolaryngol. (Impr.)

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“…A wide variety of clinical suspicion may contribute to delay in diagnosis of skin infection, which facilitates the spread of the parasite through hematogenous and/or lymphatic route, increasing the risk of installation of amastigotes in the nasooropharyngeal mucosa and the development of mucous leishmaniasis (Lambertucci et al, 2003;Nakkash-Chmaisse et al, 2011;Marra et al, 2014). It is noteworthy that this process is compounded by the institution of a treatment in time and manner inadequate.…”

Section: Discussionmentioning

confidence: 99%